tert-Butanol
Tert-Butanol (CAS: 75-65-0), also known as 2-methyl-2-propanol, is a tertiary alcohol with the molecular formula (CH3)3COH and a molar mass of 74.12 g/mol. This flammable compound serves as a crucial solvent in various chemical processes and finds applications in cell biology and nutrition research. Its distinct properties make it a valuable reagent for organic synthesis and laboratory investigations.
- IUPAC
- 2-Methyl-2-propanol,tert-Butyl alcohol,Trimethyl carbinol
- Synonyms
- 2-Methyl-2-propanoltert-Butyl alcoholTrimethyl carbinol

Solvent Applications
Tert-Butanol acts as a polar protic solvent, useful in organic reactions and as a component in solvent mixtures. Its tertiary structure influences its reactivity and solubility characteristics in chemical syntheses.
Cell Biology Research
Utilised in cell biology, Tert-Butanol may be employed in specific experimental protocols, potentially related to cryoprotection or fixation. Its solvent properties can be leveraged for cellular permeabilisation or extraction.
Nutrition Research
In nutrition research, this compound might be used in analytical procedures or as a reference standard for certain compounds. Its presence or role in biological systems is a subject of scientific investigation.
Organic Synthesis
As a tertiary alcohol, Tert-Butanol is a precursor or reagent in various organic synthesis pathways. It can participate in reactions characteristic of alcohols, albeit with steric hindrance influencing reaction rates and products.
| Molecular weight | 74.12 |
|---|---|
| Linear formula | (CH3)3COH |
| Assay | ≥98.0% |
| Grade | SAJ special grade |
| Boiling point | 83 °C(lit.) |
| Density | 0.775 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.387(lit.) |
| Melting point | 23-26 °C(lit.) |
| Vapour pressure | 31 mmHg (20 °C)44 mmHg (26 °C) |
| Vapour density | 2.5 (vs air) |
| Autoignition temp | 896 °F |


Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 11 °C / 51.8 °F |
| Transport (UN / ADR) | UN 1120 3 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-20-36/37 |
| Safety statements (S) | 9-16-46 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Expl Lim | 8 % |
|---|---|
| Availability | available only in Japan |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tert-Butanol used for?
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Tert-Butanol is primarily used as a solvent in organic synthesis and chemical processes, and it also finds applications in cell biology and nutrition research.
What is the CAS number and chemical formula for Tert-Butanol?
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The CAS number for Tert-Butanol is 75-65-0, and its linear formula is (CH3)3COH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tert-Butanol in SAJ special grade with an assay of ≥98.0%. We do not represent this product as USP, BP, or EP grade.
How should Tert-Butanol be handled safely?
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Tert-Butanol is a highly flammable liquid and vapour (H225) and can cause serious eye irritation (H319), is harmful if inhaled (H332), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area away from ignition sources.
Is Tert-Butanol available for export?
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Tert-Butanol is available only in Japan. Please contact TSS for specific export inquiries.
How can I request a sample or quote for Tert-Butanol?
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To request a sample or quote for Tert-Butanol, please contact our sales department through the TSS website or by direct inquiry.
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