Sulindac sulfide
Sulindac sulfide (CAS: 32004-67-4), with the molecular formula C20H17FO2S and a molecular weight of 340.41 g/mol, is a chemical compound supplied by Tech Serve Solutions. It is characterized by its yellow solid form and has demonstrated utility in research applications, particularly in studies involving cell survival and chemoprevention. The compound is typically supplied with an assay of ≥98% (HPLC).
- IUPAC
- (Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic acid

Cellular Research
Sulindac sulfide has been investigated for its effects on cell survival. Studies have utilized human endothelial cells, such as HMEC-1, treated with Sulindac sulfide to assess its impact on cellular viability using methods like the MTT assay.
Chemopreventive Agent Research
As a compound related to chemopreventive agents, Sulindac sulfide is a subject of interest in research exploring preventative strategies for various conditions. Its mechanism of action and efficacy are areas of ongoing scientific inquiry.
Enzyme Inhibition Studies
Sulindac sulfide is recognized as an inhibitor of cyclooxygenase enzymes. This property makes it a valuable tool in biochemical research for studying enzyme kinetics and pathways involving prostaglandin synthesis.
| Molecular weight | 340.41 |
|---|---|
| Empirical formula | C20H17FO2S |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | yellow |
| Solubility | DMSO: ≥22 mg/mL |
| Application | Human endothelial cells, HMEC-1 were treated with Sulindac sulfide and the effect on cell survival was studies by MTT assay.1 |


Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P342
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-22-42/43 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sulindac sulfide used for?
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Sulindac sulfide is used in scientific research, including studies on cell survival, chemoprevention, and enzyme inhibition, particularly related to cyclooxygenase activity.
What are the CAS number and formula for Sulindac sulfide?
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Sulindac sulfide has the CAS number 32004-67-4 and the molecular formula C20H17FO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sulindac sulfide with a purity of ≥98% as determined by HPLC. We do not represent this product as USP, BP, or EP grade.
How should Sulindac sulfide be handled?
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Sulindac sulfide is classified as dangerous. It may be harmful if swallowed, cause skin irritation, and may cause allergy or asthma symptoms or breathing difficulties if inhaled. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., N100 respirator), is required. Handle with caution in a well-ventilated area.
Is Sulindac sulfide a controlled substance?
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The provided data does not indicate that Sulindac sulfide is a controlled substance. However, users should verify local regulations.
How is Sulindac sulfide packed and shipped?
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Sulindac sulfide is typically supplied as a yellow solid. We ensure secure packaging for safe transit and export globally, adhering to all necessary regulations for chemical transport.
How can I request a quote or sample for Sulindac sulfide?
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To request a quote or a sample of Sulindac sulfide, please contact our sales department through the TSS website or by phone. Our team will assist you with your inquiry.
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