Sulforhodamine 101 acid chloride
Sulforhodamine 101 acid chloride (CAS: 82354-19-6) is a fluorescent labeling reagent with the molecular formula C31H29ClN2O6S2 and a molecular weight of 625.15 g/mol. This compound is primarily utilised for fluorescent labelling of amine groups in biochemical and molecular biology applications. It is an effective tool for protein modification and structural analysis, enabling detection and quantification through fluorescence microscopy and flow cytometry.
- IUPAC
- Sulforhodamine 101 sulfonyl chloride
- Synonyms
- Sulforhodamine 101 sulfonyl chloride

Fluorescent Labelling of Amines
Sulforhodamine 101 acid chloride readily reacts with primary amines to introduce a bright fluorescent tag. This is crucial for visualizing and tracking biomolecules in various biological assays.
Protein Modification and Analysis
Its ability to label proteins allows for detailed structural analysis and modification studies. Researchers utilise this reagent in techniques such as fluorescence microscopy and flow cytometry to understand protein function and interactions.
Biochemical and Molecular Biology Research
As a key biochemical reagent, it finds application in diverse research settings. Its fluorescent properties make it valuable for developing novel assays and probing biological systems at the molecular level.
| Molecular weight | 625.15 |
|---|---|
| Empirical formula | C31H29ClN2O6S2 |
| Storage temperature | −20°C |
| Impurities tested | ~1 mol/mol chloroform as solvent of crystallization |
| Composition | Dye content, ~75% |


Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H351Suspected of causing cancer
- H361D
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P281Use personal protective equipment as required
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-40-48/20/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 586 nm; λem 605 nm in H2O |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sulforhodamine 101 acid chloride used for?
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Sulforhodamine 101 acid chloride is used for fluorescent labelling of amine groups, enabling applications in protein modification, structural analysis, fluorescence microscopy, and flow cytometry within biochemical and molecular biology research.
What is the CAS number and formula for Sulforhodamine 101 acid chloride?
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The CAS number is 82354-19-6 and the empirical formula is C31H29ClN2O6S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sulforhodamine 101 acid chloride with a dye content of approximately 75%, and it contains approximately 1 mol/mol of chloroform as a solvent of crystallisation. We do not represent this product as USP, BP, or EP grade.
How should Sulforhodamine 101 acid chloride be handled safely?
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Sulforhodamine 101 acid chloride is a Warning substance. It may cause skin irritation (H315), serious eye irritation (H319), is suspected of causing cancer (H351), and may cause harm to the unborn child (H361d). It may also cause damage to organs through prolonged or repeated exposure (H373). Wear protective gloves, eye protection, and protective clothing. Avoid exposure and ensure adequate ventilation. Store at -20°C.
Is Sulforhodamine 101 acid chloride a controlled substance?
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The provided data does not indicate that Sulforhodamine 101 acid chloride is a controlled substance.
How is Sulforhodamine 101 acid chloride packed and shipped?
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Sulforhodamine 101 acid chloride is typically stored at -20°C. Specific packing and shipping details for export will be provided upon request, adhering to all relevant regulations.
How can I request a sample or quote for Sulforhodamine 101 acid chloride?
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To request a sample or quote, please contact Tech Serve Solutions directly through our website or sales department. Our team will be pleased to assist you with your inquiry.
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