SU5614

CAS 1055412-47-9C15H13ClN2OCell Biology

SU5614 (CAS: 1055412-47-9; Formula: C15H13ClN2O) is an orange crystalline powder with a molecular weight of 272.73. This compound functions as a potent and selective inhibitor of receptor tyrosine kinases (RTKs). It is primarily utilised in biochemical research for investigating cellular signalling pathways, particularly those involving receptor tyrosine kinase biology and inhibition. SU5614 is an valuable tool for understanding cancer biology and developing novel therapeutic strategies.

IUPAC: (3Z)-5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
Synonyms: (3Z)-5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one

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SU5614 (C15H13ClN2O) — chemical structure, CAS 1055412-47-9; Life Science, fine chemical supplied by Tech Serve Solutions

Cell BiologyKinase/Phosphatase BiologyPfizer CompoundsTyrosine Kinase (TK) More...

01 /Applications

Receptor Tyrosine Kinase (RTK) Inhibition

SU5614 is a potent inhibitor of various receptor tyrosine kinases, making it a critical tool for studying RTK signaling pathways in cell biology. Its selectivity allows researchers to probe specific kinase activities.

Cell Signaling Research

This compound is instrumental in understanding complex cell signaling cascades, particularly in neuroscience and cancer research. It helps elucidate the downstream effects of RTK activation and inhibition.

Drug Discovery and Development

As a compound associated with Pfizer, SU5614 serves as a valuable research chemical in early-stage drug discovery efforts targeting kinase-driven diseases. Its characteristics aid in the development of novel therapeutics.

02 /Properties

Molecular weight	272.73
Empirical formula	C15H13ClN2O
Assay	≥98% (HPLC)
Form	powder
Colour	orange
Solubility	DMSO: ≥20 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

Hazard statements

H413May cause long-lasting harmful effects to aquatic life

Water hazard class (WGK, DE)	3
Risk statements (R)	53

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1055412-47-9

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is SU5614 used for?

SU5614 is used in biochemical research as a potent and selective inhibitor of receptor tyrosine kinases (RTKs), aiding in the study of cell signaling pathways, particularly in cancer biology and neuroscience.

What are the CAS number and formula for SU5614?

The CAS number for SU5614 is 1055412-47-9, and its molecular formula is C15H13ClN2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies SU5614 with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling considerations for SU5614?

SU5614 is classified with hazard statement H413, indicating it may cause long lasting harmful effects to aquatic life. It is recommended to handle this compound with appropriate personal protective equipment and to avoid release into the environment. Please consult the Safety Data Sheet (SDS) for full details.

How is SU5614 packaged, shipped, and exported?

SU5614 is typically supplied as an orange powder and stored at 2-8°C. As a global supplier, Tech Serve Solutions is experienced in exporting fine chemicals worldwide, adhering to all relevant shipping regulations.

How can I request a sample or quote for SU5614?

To request a sample or a quotation for SU5614, please contact our sales team via the website or direct email, providing your specific requirements and shipping details.