Sodium taurodeoxycholate hydrate
Sodium taurodeoxycholate hydrate (CAS: 207737-97-1) is an anionic detergent with the chemical formula C26H44NO6SNa. Derived from bile salts, it is primarily utilised for its detergent properties in biochemical research. Its key application involves the isolation of membrane proteins, particularly those found within the inner mitochondrial membrane, owing to its effectiveness in solubilising these complex structures.
- IUPAC
- 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid,Taurodeoxycholic acid sodium salt hydrate
Detergent for Membrane Protein Isolation
This bile salt is an effective anionic detergent for solubilising membrane proteins. It is specifically noted for its use in the isolation of inner mitochondrial membrane proteins, aiding in their extraction and purification for further study.
Biochemical Research Reagent
As a naturally occurring bile salt, it serves as a valuable reagent in various biochemical research applications. Its surfactant properties are leveraged in studies requiring the disruption and solubilisation of biological membranes.
Chiral Synthesis Applications
The compound's chiral nature makes it a useful building block in asymmetric synthesis. It can be employed in the development of complex molecules where specific stereochemistry is required.
| Molecular weight | 521.69 (anhydrous basis) |
|---|---|
| Linear formula | C26H44NO6SNa |
| Assay | 95% |
| Solubility | H2O: soluble0.5 M, clear, colorless to faintly yellow |
| Optical activity | [α]25/D +33°, c = 2.5 in H2O |
| Impurities tested | ≤0.002% Phosphorus (P)≤0.1% Insoluble matter |
| Application | Bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. |
| Melting point | 168 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Cation traces | Al: ≤0.0005%Ca: ≤0.005%Cu: ≤0.0005%Fe: ≤0.0005%K: ≤0.01%Mg: ≤0.005%NH4+: ≤0.05%Pb: ≤0.001%Zn: ≤0.0005% |
| Anion traces | chloride (Cl-): ≤0.5%sulfate (SO42-): ≤0.05% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | micellar avg mol wt 3100 |
|---|---|
| Aggregation Number | 6 |
| Cmc | 1-4 mM(20-25°C) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium taurodeoxycholate hydrate used for?
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Sodium taurodeoxycholate hydrate is an anionic detergent used for the isolation of membrane proteins, including those from the inner mitochondrial membrane. It also finds applications in asymmetric synthesis and general chemical synthesis.
What is the CAS number and chemical formula?
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The CAS number is 207737-97-1 and the chemical formula is C26H44NO6SNa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium taurodeoxycholate hydrate with a purity of 95%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a NIOSH (US) or EN143 (EU) approved respirator filter (type N95 or P1 respectively) if airborne exposure is likely. Refer to the safety data sheet for comprehensive information.
Is Sodium taurodeoxycholate hydrate a controlled substance?
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The provided data does not indicate that Sodium taurodeoxycholate hydrate is a controlled substance.
How is this product packed, shipped, and exported?
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Products are carefully packed according to international shipping regulations to ensure integrity during transit. TSS is experienced in exporting fine chemicals globally.
How can I request a sample or quote?
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Please contact our sales team via the website or phone to request a sample or a personalised quote for Sodium taurodeoxycholate hydrate.
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