Sodium glycodeoxycholate

CAS 16409-34-0C26H42NNaO5Biochemicals & Reagents

Sodium glycodeoxycholate (CAS: 16409-34-0) is an anionic bile salt with the molecular formula C26H42NNaO5 and a molecular weight of 471.61. It is utilized as a biological detergent and finds application in research settings. Its properties make it valuable for studies involving intestinal fluid mimetics and the investigation of calcium buffering by bile salt micelles, contributing to biochemical and membrane protein research.

IUPAC: 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide,Glycodeoxycholic acid sodium salt,Glycodesoxycholic acid,N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine
Synonyms: Glycodeoxycholic acid sodium saltGlycodesoxycholic acidN-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine

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Sodium glycodeoxycholate (C26H42NNaO5) — chemical structure, CAS 16409-34-0; Life Science, fine chemical supplied by Tech Serve Solutions

Anionic DetergentsBile SaltsBiochemicals and ReagentsCell CultureDetergentsDetergents N to ZDetergents by ApplicationsEnzymology

01 /Applications

Mimetic Intestinal Fluid Development

Sodium glycodeoxycholate has been employed in research to create artificial intestinal fluids that more closely mimic physiological conditions compared to traditional mixed bile salt systems. This aids in studying gastrointestinal processes and drug absorption.

Calcium Buffering Studies

This bile salt has been used in investigations to understand the capacity of bile salt micelles to buffer calcium ions. Such research is fundamental to comprehending physiological processes involving bile salts and mineral homeostasis.

Biochemical Research and Reagents

As a biochemical reagent, sodium glycodeoxycholate serves as a valuable tool in various laboratory investigations. Its detergent properties are particularly useful in cell culture and membrane protein solubilization studies.

02 /Properties

Molecular weight	471.61
Empirical formula	C26H42NNaO5
Assay	≥97% (TLC)
Solubility	H2O: soluble0.1 M, clear, colorless
Impurities tested	≤0.001% Phosphorus (P)≤0.1% Insoluble matter
Application	Sodium glycodeoxycholate has been used in a study to develop more similar mimetic intestinal fluids to physiological fluids than those developed by mixed bile salt systems (MBS). 1 It has also been used in a study to investigate Ca2+ buffering capability of bile salt micelles. 2

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36
Cation traces	Al: ≤0.0005%Ca: ≤0.005%Cu: ≤0.0005%Fe: ≤0.001%K: ≤0.005%Mg: ≤0.001%NH4+: ≤0.05%Pb: ≤0.001%Zn: ≤0.0005%
Anion traces	chloride (Cl-): ≤1%sulfate (SO42-): ≤0.05%

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

16409-34-0

MDL number

MFCD00036742

PubChem substance

24895386

05 /Additional specifications

Description	anionic
Product Line	BioXtra

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Sodium glycodeoxycholate used for?

Sodium glycodeoxycholate is used in biochemical research, including the development of mimetic intestinal fluids and studies on calcium buffering by bile salt micelles. It also serves as an anionic detergent for applications such as membrane protein solubilization.

What are the CAS number and formula for Sodium glycodeoxycholate?

The CAS number for Sodium glycodeoxycholate is 16409-34-0, and its empirical formula (Hill notation) is C26H42NNaO5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Sodium glycodeoxycholate with a minimum purity of ≥97% (TLC). This product is not supplied as USP, BP, or EP grade.

How should Sodium glycodeoxycholate be handled safely?

Sodium glycodeoxycholate is a warning hazardous substance that may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). When handling, use a dust mask type N95 (US), wear eyeshields and gloves, and ensure adequate ventilation. Avoid breathing dust.

Is Sodium glycodeoxycholate a controlled substance?

The provided data does not indicate that Sodium glycodeoxycholate is a controlled substance.

How is Sodium glycodeoxycholate packed, shipped, and exported?

Tech Serve Solutions securely packs and exports chemicals globally, adhering to all relevant shipping regulations. Specific packaging details depend on quantity and destination.