Sibutramine hydrochloride monohydrate
Sibutramine hydrochloride monohydrate (CAS 125494-59-9) is a chemical compound with the formula C17H26ClN · HCl · H2O and a molecular weight of 334.32 g/mol. Supplied as a white solid, this substance is primarily utilised as an analytical standard. It has been employed in the screening of dietary supplements for the presence of sibutramine using techniques such as ion mobility spectrometry. Tech Serve Solutions provides this reagent for research purposes.
- IUPAC
- 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate,Meridia,Reductil
- Synonyms
- 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrateMeridiaReductil

Analytical Standard
Sibutramine hydrochloride monohydrate serves as a critical reference standard in analytical chemistry. It is used for the accurate identification and quantification of sibutramine in various matrices, particularly in the quality control of dietary supplements.
Chromatographic Analysis
This compound is employed in chromatographic methods, such as High-Performance Liquid Chromatography (HPLC), to ensure assay validation and method development. Its purity, specified as ≥98%, makes it suitable for reliable analytical results.
Screening of Illicit Substances
It has been documented for use in screening dietary supplements for undeclared sibutramine. For example, it was used as a standard in ion mobility spectrometry for such screening purposes, aiding regulatory bodies and researchers.
| Molecular weight | 334.32 |
|---|---|
| Empirical formula | C17H26ClN · HCl · H2O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >30 mg/mLH2O: insoluble |
| Storage temperature | room temp |
| Application | Sibutramine hydrochloride monohydrate was used as standard to screen dietary supplements for sibutramine using ion mobility spectrometer.1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule IV |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sibutramine hydrochloride monohydrate used for?
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Sibutramine hydrochloride monohydrate is primarily used as an analytical standard for the detection and quantification of sibutramine, notably in the screening of dietary supplements.
What is the CAS number and formula for Sibutramine hydrochloride monohydrate?
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The CAS number is 125494-59-9, and the empirical formula (Hill notation) is C17H26ClN · HCl · H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sibutramine hydrochloride monohydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade; it is supplied for research and laboratory use.
How should Sibutramine hydrochloride monohydrate be handled safely?
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For safe handling, use appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany rating of 3, indicating a high hazard to water.
Is Sibutramine hydrochloride monohydrate a controlled substance?
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Yes, Sibutramine hydrochloride monohydrate is listed under USDEA Schedule IV, indicating it is a controlled substance.
How is Sibutramine hydrochloride monohydrate typically shipped and exported?
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Sibutramine hydrochloride monohydrate is supplied as a white solid and is stored at room temperature. As a global supplier, TSS adheres to all regulations for the export of such chemicals.
How can I request a quote or sample?
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To request a quote or sample of Sibutramine hydrochloride monohydrate, please contact our sales department through the website or via direct inquiry.
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