Sandoz 58-035
Sandoz 58-035 (CAS: 78934-83-5), a silyl derivative with the formula C30H47NOSi and a molecular weight of 465.79 g/mol, is a white powder. This compound is primarily utilised in biological research for its ability to induce simultaneous activation of the unfolded protein response (UPR) and pattern recognition receptors (PRRs) in experimental models, such as mouse peritoneal macrophages. Its specific applications lie in cellular signalling and cholesterol metabolism studies.
- IUPAC
- 3-[Decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenethyl]propanamide,SA 58-035
- Synonyms
- 3-[Decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenethyl]propanamide,SA 58-035
Induction of UPR and PRR Activation
Sandoz 58-035 has been employed in research settings to trigger the unfolded protein response (UPR) and pattern recognition receptors (PRRs) concurrently. This effect has been observed in experimental models, specifically in mouse peritoneal macrophages, facilitating studies on cellular stress responses.
Cellular Signalling Research
As a bioactive small molecule, Sandoz 58-035 serves as a valuable tool in cell biology and cell signalling research. Its mechanism of action provides insights into the complex interplay between cellular stress pathways and immune receptor activation.
Cholesterol Metabolism Studies
The compound's involvement in pathways related to cholesterol metabolism makes it useful for researchers investigating lipid regulation and its consequences. It can be used to probe the effects of cellular perturbation on lipid homeostasis.
| Molecular weight | 465.79 |
|---|---|
| Empirical formula | C30H47NOSi |
| Assay | >98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: soluble16 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Application | Sandoz 58-035 was used to induce simultaneous activation of unfolded protein response (UPR) and pattern recognition receptors (PRRs) in mouse peritoneal macrophages.3 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... SOAT1(6646)rat ... Soat1(81782) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sandoz 58-035 used for?
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Sandoz 58-035 is used in research to induce simultaneous activation of the unfolded protein response (UPR) and pattern recognition receptors (PRRs) in cell models, and for studies related to cholesterol metabolism and cell signalling.
What are the CAS number and formula for Sandoz 58-035?
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The CAS number for Sandoz 58-035 is 78934-83-5, and its empirical formula is C30H47NOSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sandoz 58-035 with a purity of >98% (HPLC). This product is intended for research and laboratory use, and is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for Sandoz 58-035?
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Handling Sandoz 58-035 requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany rating of 3, indicating it is hazardous.
How is Sandoz 58-035 shipped and exported?
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Sandoz 58-035 is typically stored at 2-8°C. As a global supplier, Tech Serve Solutions exports this chemical worldwide, adhering to all relevant shipping and customs regulations.
How can I request a sample or quote for Sandoz 58-035?
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To request a sample or quote for Sandoz 58-035, please contact our sales team via the website or your designated account manager. Please provide your contact details and the quantity required.
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