(S,S)-2,3-Bis(tert-butylmethylphosphino)quinoxaline
(S,S)-2,3-Bis(tert-butylmethylphosphino)quinoxaline (CAS 1107608-80-9) is a chiral phosphine ligand with the molecular formula C18H28N2P2 and a molecular weight of 334.38 g/mol. This compound is instrumental in asymmetric synthesis, serving as a key component in catalytic systems. Its specific stereochemistry enables the selective formation of chiral products, making it valuable in the development of complex molecules within the pharmaceutical and fine chemical industries.
- IUPAC
- (S) QuinoxP®
- Synonyms
- 1107608-80-9, C18H28N2P2, (S) QuinoxP®

Asymmetric Catalysis
This chiral ligand is employed in transition metal catalysis to facilitate enantioselective transformations. It enables the synthesis of specific enantiomers crucial for pharmaceutical and agrochemical development.
Chiral Ligand Synthesis
As a member of the QuinoxP* ligand family, it is used in the design and synthesis of novel catalytic systems for challenging asymmetric reactions.
Research and Development
It serves as a valuable tool in academic and industrial research laboratories for exploring new synthetic methodologies and developing advanced materials.
| Molecular weight | 334.38 |
|---|---|
| Empirical formula | C18H28N2P2 |
| Optical activity | [α]22/D +55°, c = 1 in chloroform |
| Melting point | 100-105 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S,S)-2,3-Bis(tert-butylmethylphosphino)quinoxaline primarily used for?
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(S,S)-2,3-Bis(tert-butylmethylphosphino)quinoxaline is primarily used as a chiral ligand in asymmetric synthesis and catalysis.
What is the CAS number and molecular formula for this compound?
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The CAS number is 1107608-80-9, and the molecular formula is C18H28N2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and development purposes. The exact assay and purity are detailed on the product's specification sheet. We do not represent this product as USP, BP, or EP grade.
How should (S,S)-2,3-Bis(tert-butylmethylphosphino)quinoxaline be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust, and ensure adequate ventilation. It is classified as harmful if swallowed and causes skin and eye irritation.
Is this chemical packed and shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S,S)-2,3-Bis(tert-butylmethylphosphino)quinoxaline. It is shipped according to UN 2811, Class 6.1 regulations.
How can I request a sample or a quote for this chemical?
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Please contact our sales team via our website or direct email to request a sample or obtain a quotation for (S,S)-2,3-Bis(tert-butylmethylphosphino)quinoxaline.
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