(S)-N-Fmoc-piperidine-2-carboxylic acid

CAS 86069-86-5C21H21NO4Chemical Synthesis

(S)-N-Fmoc-piperidine-2-carboxylic acid (CAS 86069-86-5) is a chiral heterocyclic building block with the molecular formula C21H21NO4 and a molecular weight of 351.40 g/mol. This compound is primarily utilised in asymmetric synthesis and peptide chemistry, serving as a valuable intermediate for the construction of complex molecules. Its optically active nature makes it essential for stereoselective syntheses in pharmaceutical research and development.

IUPAC: (S)-1-Fmoc-piperidine-2-carboxylic acid,N-Fmoc-L-pipecolinic acid,Fmoc-Pip-OH
Synonyms: N-Fmoc-L-pipecolinic acid(S)-1-Fmoc-piperidine-2-carboxylic acidFmoc-Pip-OH

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(S)-N-Fmoc-piperidine-2-carboxylic acid (C21H21NO4) — chemical structure, CAS 86069-86-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical BiologyChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksOthersPeptide ChemistryPiperidines

01 /Applications

Chiral Building Block in Asymmetric Synthesis

This molecule acts as a key chiral synthon for introducing stereocenters in complex organic molecules. It is particularly useful in the synthesis of pharmaceuticals and other biologically active compounds where precise stereochemistry is crucial.

Peptide Chemistry and Unnatural Amino Acids

As an unnatural amino acid derivative, it can be incorporated into peptides to modify their structure and properties. This application is important for developing novel peptidomimetics and therapeutic peptides.

Heterocyclic Synthesis

The piperidine core of the molecule makes it a useful precursor for the synthesis of various nitrogen-containing heterocyclic compounds. These structures are common in many drug candidates and natural products.

02 /Properties

Molecular weight	351.40
Empirical formula	C21H21NO4
Assay	97%
Optical activity	[α]22/D −23°, c = 1 in DMF
Storage temperature	2-8°C
Melting point	153-158 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Transport (UN / ADR)	UN 3077 9 / PGIII
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

86069-86-5

Beilstein registry

4718405

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-N-Fmoc-piperidine-2-carboxylic acid used for?

(S)-N-Fmoc-piperidine-2-carboxylic acid is used as a chiral building block in asymmetric synthesis, in peptide chemistry for unnatural amino acid derivatives, and in the synthesis of heterocyclic compounds.

What are the CAS number and formula for (S)-N-Fmoc-piperidine-2-carboxylic acid?

The CAS number is 86069-86-5, and the empirical formula is C21H21NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

How should (S)-N-Fmoc-piperidine-2-carboxylic acid be handled and stored?

Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 or P1 respirator filter. Store at 2-8°C.

Is (S)-N-Fmoc-piperidine-2-carboxylic acid a controlled substance?

This compound is classified under UN 3077, Hazard Class 9, Packing Group III. Please refer to specific regional regulations for controlled substance status.