(S)-N-Boc-2-methylpyrrolidine
(S)-N-Boc-2-methylpyrrolidine (CAS: 137496-71-0, C10H19NO2) is a chiral heterocyclic compound with a molecular weight of 185.26 g/mol. This tert-butyl carbamate protected pyrrolidine derivative serves as a valuable chiral building block in asymmetric synthesis. Its stereochemistry and functional groups make it an important intermediate for creating complex chiral molecules, particularly within the pharmaceutical and fine chemical industries.
- IUPAC
- (S)-2-Methylpyrrolidine-1-carboxylic acid-tert-butyl ester
- Synonyms
- (S)-2-Methylpyrrolidine-1-carboxylic acid tert-butyl ester

Chiral Building Block
Utilised in the synthesis of enantiomerically pure compounds. Its defined stereocentre is crucial for constructing stereospecific target molecules.
Asymmetric Synthesis
Serves as a key intermediate in stereoselective reactions, enabling the creation of complex chiral structures with high enantiomeric purity.
Pharmaceutical Intermediates
A foundational component in the development pathways for various active pharmaceutical ingredients (APIs) where chirality is critical.
Heterocyclic Chemistry
Incorporated into synthetic routes requiring substituted pyrrolidine rings, contributing to the diversity of heterocyclic compounds.
| Molecular weight | 185.26 |
|---|---|
| Empirical formula | C10H19NO2 |
| Assay | 95% |
| Density | 0.962 g/mL at 25 °C |
| Refractive index | n20/D 1.444 |



Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | UN 2810 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-37/38-41-50 |
| Safety statements (S) | 26-39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-N-Boc-2-methylpyrrolidine used for?
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(S)-N-Boc-2-methylpyrrolidine is primarily used as a chiral building block in asymmetric synthesis, particularly for the preparation of pharmaceutical intermediates and other complex chiral molecules.
What is the CAS number and formula for (S)-N-Boc-2-methylpyrrolidine?
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The CAS number is 137496-71-0, and the empirical formula is C10H19NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-N-Boc-2-methylpyrrolidine with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should (S)-N-Boc-2-methylpyrrolidine be handled safely?
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This compound is a Danger hazard. It is harmful if swallowed (H301), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). It is also toxic to aquatic life with long-lasting effects (H400). Appropriate personal protective equipment including eyeshields, gloves, and respiratory protection (e.g., type ABEK respirator filter) is essential. Handle in a well-ventilated area and avoid release to the environment.
How is (S)-N-Boc-2-methylpyrrolidine packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals in compliance with all relevant international regulations for hazardous materials. Specific details regarding UN 2810, 6.1/PG 3 classification apply.
How can I request a sample or quote for (S)-N-Boc-2-methylpyrrolidine?
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To request a sample or a quote, please contact our sales team via the website or direct inquiry, providing your specific requirements and shipping details.
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