S-(−)-Eticlopride hydrochloride

CAS 97612-24-3C17H25ClN2O3 · HClBiochemicals & Reagents

S-(−)-Eticlopride hydrochloride (CAS: 97612-24-3) is a potent and selective dopamine D2 receptor antagonist. With the molecular formula C17H25ClN2O3 · HCl and a molecular weight of 377.31 g/mol, this off-white powder is primarily utilised in neuroscience research. It serves as a crucial tool for investigating dopaminergic neurotransmission and the function of D2 receptors in various physiological and pathological processes.

IUPAC: FLB 131,S-(−)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride

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S-(−)-Eticlopride hydrochloride (C17H25ClN2O3 · HCl) — chemical structure, CAS 97612-24-3; Life Science, fine chemical supplied by Tech Serve Solutions

AntagonistsBioactive Small MoleculesBiochemicals and ReagentsCell BiologyDopaminargics - AntagonistsDopaminergicsGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuroscience

01 /Applications

Dopamine D2 Receptor Antagonism

S-(−)-Eticlopride hydrochloride is a selective antagonist of dopamine D2 receptors, making it invaluable for studying the role of these receptors in neurotransmission and brain function. Its selectivity allows researchers to probe specific dopaminergic pathways.

Neuroscience Research Tool

This compound is widely employed in neuroscience to investigate conditions associated with dopaminergic system dysregulation, such as schizophrenia, Parkinson's disease, and addiction. It aids in understanding receptor binding and downstream signalling.

Pharmacological Studies

As a well-characterised antagonist, it serves as a reference compound in pharmacological assays to identify and characterise novel dopaminergic agents. Its known binding affinity and selectivity provide a benchmark for new drug discovery efforts.

02 /Properties

Molecular weight	377.31
Empirical formula	C17H25ClN2O3 · HCl
Assay	≥98% (HPLC)
Form	powder
Colour	off-white
Solubility	H2O: soluble >10 mg/mLethanol: soluble2.6 mg/mL0.1 M HCl: soluble7 mg/mL
Optical activity	[α]27/D −7.2°, c = 0.3 in methanol(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

97612-24-3

MDL number

MFCD00055132

05 /Additional specifications

Gene Information	human ... DRD2(1813)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is S-(−)-Eticlopride hydrochloride used for?

S-(−)-Eticlopride hydrochloride is primarily used as a selective dopamine D2 receptor antagonist in neuroscience research to study dopaminergic neurotransmission and related pathways.

What is the CAS number and molecular formula for S-(−)-Eticlopride hydrochloride?

The CAS number is 97612-24-3 and the molecular formula is C17H25ClN2O3 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies S-(−)-Eticlopride hydrochloride with an assay of ≥98% (HPLC). This is a research-grade chemical and is not supplied as USP, BP, EP, pharmacopoeia, nutraceutical, or food grade.

What are the safety and handling recommendations for S-(−)-Eticlopride hydrochloride?

When handling S-(−)-Eticlopride hydrochloride, it is essential to use personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.

Is S-(−)-Eticlopride hydrochloride a controlled substance?

The provided data does not indicate that S-(−)-Eticlopride hydrochloride is a controlled substance.

How is S-(−)-Eticlopride hydrochloride packed and shipped?

S-(−)-Eticlopride hydrochloride is typically supplied as an off-white powder. Tech Serve Solutions is a global supplier and exporter, adhering to all regulations for safe and compliant shipment.