S-(5′-Adenosyl)-L-methionine iodide
S-(5′-Adenosyl)-L-methionine iodide (CAS 3493-13-8), with the molecular formula C15H23IN6O5S, is a crucial biological molecule. It functions as a primary methyl donor in mammalian cell culture and is an intermediate in methionine biosynthesis. This compound is derived from yeast and supplied by Tech Serve Solutions for research and biochemical applications, offering essential support for cellular methylation processes and metabolic studies.
- IUPAC
- AdoMet,SAM

Mammalian Cell Culture
S-(5′-Adenosyl)-L-methionine iodide serves as a vital methyl donor in mammalian cell culture systems. It supports essential cellular methylation reactions, crucial for DNA, RNA, and protein modifications, thereby maintaining cellular health and function.
Methionine Biosynthesis Research
This compound is involved in the initial step of methionine biosynthesis. Researchers utilise it to investigate metabolic pathways and the enzymatic reactions governing amino acid synthesis in biological systems.
Biochemical Research
As a key biochemical reagent, S-(5′-Adenosyl)-L-methionine iodide is used in various in vitro studies. Its role as a methyl donor makes it valuable for exploring enzymatic mechanisms and cellular signalling pathways.
| Molecular weight | 526.35 |
|---|---|
| Empirical formula | C15H23IN6O5S |
| Assay | ≥80% (HPLC)≥80% (spectrophotometric assay) |
| Solubility | H2O: soluble100 mg/mL |
| Storage temperature | −20°C |
| Application | S-(5′-Adenosyl)-L-methionine (SAM, AdoMet) is used as a primary methyl donor molecule in mammalian cell culture and the first step metabolite in methionine biosynthesis. |
| Biological source | from yeast |

Hazard statements
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S-(5′-Adenosyl)-L-methionine iodide used for?
+
S-(5′-Adenosyl)-L-methionine iodide is primarily used as a methyl donor in mammalian cell culture and as a metabolite in methionine biosynthesis research. It is also employed as a general biochemical reagent for in vitro studies.
What are the CAS number and molecular formula?
+
The CAS number for S-(5′-Adenosyl)-L-methionine iodide is 3493-13-8, and its empirical formula (Hill notation) is C15H23IN6O5S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies S-(5′-Adenosyl)-L-methionine iodide with an assay of ≥80% by HPLC and ≥80% by spectrophotometric assay. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should S-(5′-Adenosyl)-L-methionine iodide be handled safely?
+
Based on GHS information, S-(5′-Adenosyl)-L-methionine iodide may cause an allergic skin reaction (H317). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a type N95 respirator filter, should be used. Handle with caution and avoid skin contact.
How is this chemical shipped?
+
S-(5′-Adenosyl)-L-methionine iodide is shipped on dry ice to maintain its required storage temperature of -20°C.
How can I request a quote or sample?
+
To request a quote or a sample of S-(5′-Adenosyl)-L-methionine iodide, please contact our sales team via the website or direct inquiry channels.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis