S-Acetylthioglycolic acid N-hydroxysuccinimide ester
S-Acetylthioglycolic acid N-hydroxysuccinimide ester (CAS 76931-93-6; C8H9NO5S; MW 231.23) is a versatile organic building block. This protected thiol derivative is primarily used in chemical synthesis, particularly for introducing protected acetylthioglycolic acid moieties into molecules. Its structure facilitates controlled reactions, making it valuable in research and development settings for creating complex organic compounds.
- IUPAC
- N-Succinimidyl (acetylthio)acetate,N-Succinimidyl S-acetylthioglycolate,S-Acetylthioglycolic acid NHS ester
- Synonyms
- N-Succinimidyl (acetylthio)acetateN-Succinimidyl S-acetylthioglycolateS-Acetylthioglycolic acid NHS ester
Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of complex organic molecules. Its N-hydroxysuccinimide ester functionality allows for facile coupling reactions under mild conditions.
Bioconjugation Reagent
Can be employed in bioconjugation strategies for modifying biomolecules. The acetylthio group offers a protected thiol that can be deprotected for subsequent reactions like maleimide conjugation.
Peptide Chemistry
Useful in peptide synthesis for introducing modified amino acid residues or for derivatizing peptides. The protected thiol can be selectively deprotected and reacted.
Research and Development
A valuable reagent for academic and industrial research laboratories exploring new synthetic pathways and developing novel chemical entities. Its specific reactivity profile aids in targeted molecular design.
| Molecular weight | 231.23 |
|---|---|
| Empirical formula | C8H9NO5S |
| Assay | ≥95% (TLC) |
| Solubility | acetonitrile: soluble50 mg/mLDMF: soluble |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S-Acetylthioglycolic acid N-hydroxysuccinimide ester used for?
+
S-Acetylthioglycolic acid N-hydroxysuccinimide ester (CAS 76931-93-6) is used as an intermediate in organic synthesis, for bioconjugation, and in peptide chemistry to introduce protected thiol functionalities.
What is the CAS number and formula for S-Acetylthioglycolic acid N-hydroxysuccinimide ester?
+
The CAS number is 76931-93-6 and the empirical formula is C8H9NO5S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies S-Acetylthioglycolic acid N-hydroxysuccinimide ester with an assay of ≥95% (TLC). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should S-Acetylthioglycolic acid N-hydroxysuccinimide ester be handled and stored?
+
Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 respirator filter is recommended. Store at -20°C.
Is S-Acetylthioglycolic acid N-hydroxysuccinimide ester available for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including S-Acetylthioglycolic acid N-hydroxysuccinimide ester.
How can I request a quote or sample?
+
Please contact our sales team via the website or direct email to request a quote or sample for S-Acetylthioglycolic acid N-hydroxysuccinimide ester.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis