(S)-3-(Boc-amino)-2-methylpropionic acid
(S)-3-(Boc-amino)-2-methylpropionic acid (CAS: 190897-47-3) is a chiral building block with a molecular weight of 203.24 g/mol. This unnatural amino acid derivative is protected with a tert-butyloxycarbonyl (Boc) group, making it valuable in peptide synthesis and chemical biology. Its specific stereochemistry and functional groups allow for precise molecular construction in advanced chemical research and development.
- IUPAC
- (S)-Boc-β2-Homoala-OH
- Synonyms
- (S)-Boc-beta-2-homoalanine
Peptide Synthesis
This Boc-protected amino acid is used as a non-proteinogenic building block in the synthesis of modified peptides. It allows for the introduction of specific structural or functional properties into peptide sequences.
Chemical Biology Research
Its unique structure finds application in the design and synthesis of novel biomolecules and probes for studying biological systems. The unnatural amino acid can be incorporated into peptides to alter their stability, activity, or localization.
Chiral Synthesis
As a chiral compound, it serves as a valuable intermediate in asymmetric synthesis. The defined stereocenter is crucial for building complex chiral molecules with specific optical properties.
Drug Discovery
This compound can be utilized in the development of new pharmaceutical agents. Its incorporation into potential drug candidates may influence pharmacokinetic or pharmacodynamic properties.
| Molecular weight | 203.24 |
|---|---|
| Linear formula | (CH3)3CO2CNHCH2CH(CH3)CO2H |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +12±2°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 88 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-3-(Boc-amino)-2-methylpropionic acid used for?
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It is primarily used as a chiral building block in peptide synthesis, chemical biology research, and asymmetric synthesis, particularly in the development of modified peptides and novel biomolecules.
What are the CAS number and molecular formula?
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The CAS number is 190897-47-3. The linear formula is (CH3)3CO2CNHCH2CH(CH3)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.
How should (S)-3-(Boc-amino)-2-methylpropionic acid be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 or P1 respirator filter is recommended. Store at 2-8°C.
Is this compound a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How are your chemicals packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Products are packaged according to safety regulations for international transport. Please contact us for specific shipping inquiries.
How can I request a sample or quote?
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Please contact our sales team or use the online inquiry form to request a sample or a quotation for (S)-3-(Boc-amino)-2-methylpropionic acid.
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