(S)-3,4-Dimethoxy-α-methylbenzylamine
(S)-3,4-Dimethoxy-α-methylbenzylamine (CAS: 65451-89-0), a chiral amine with the molecular formula C10H15NO2, is an essential organic building block. It is frequently utilised in asymmetric synthesis and broader chemical synthesis applications. Supplied by Tech Serve Solutions, this compound is known for its high optical purity, making it valuable for stereoselective reactions in research and development settings. Its structure features methoxy groups on the phenyl ring, contributing to its reactivity.
- IUPAC
- (S)-1-(3,4-Dimethoxyphenyl)ethylamine
- Synonyms
- (S)-1-(3,4-Dimethoxyphenyl)ethylamine

Chiral Auxiliary in Asymmetric Synthesis
This enantiomerically pure amine serves as a valuable chiral auxiliary, enabling the stereoselective synthesis of complex molecules. Its specific configuration facilitates the control of stereochemistry in various organic transformations.
Intermediate in Pharmaceutical Synthesis
As a chiral building block, (S)-3,4-Dimethoxy-α-methylbenzylamine is employed in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its presence can be critical for achieving the desired therapeutic enantiomer.
Precursor for Specialty Chemicals
The compound can act as a precursor for a range of specialty organic chemicals. Its unique dimethoxy-substituted benzylamine structure offers versatile reactivity for further functionalisation.
| Molecular weight | 181.23 |
|---|---|
| Empirical formula | C10H15NO2 |
| Assay | ≥98.5% (GC)99% |
| Optical purity | enantiomeric excess: ≥98.5% |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-52 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-3,4-Dimethoxy-α-methylbenzylamine used for?
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(S)-3,4-Dimethoxy-α-methylbenzylamine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the synthesis of pharmaceuticals and other specialty organic chemicals.
What is the CAS number and molecular formula for (S)-3,4-Dimethoxy-α-methylbenzylamine?
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The CAS number for (S)-3,4-Dimethoxy-α-methylbenzylamine is 65451-89-0, and its molecular formula is C10H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-3,4-Dimethoxy-α-methylbenzylamine with an assay of ≥98.5% (GC) and an enantiomeric excess of ≥98.5%. This compound is not represented as USP, BP, or EP grade.
How should (S)-3,4-Dimethoxy-α-methylbenzylamine be handled?
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This compound causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Ensure adequate ventilation. In case of contact, rinse immediately with plenty of water and seek medical advice.
Is (S)-3,4-Dimethoxy-α-methylbenzylamine subject to special shipping regulations?
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Yes, (S)-3,4-Dimethoxy-α-methylbenzylamine is shipped as UN 2735, Amines, liquid, corrosive, n.o.s. (contains (S)-1-(3,4-Dimethoxyphenyl)ethylamine), 8, PG II.
How can I request a sample or quote for (S)-3,4-Dimethoxy-α-methylbenzylamine?
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To request a sample or a quotation, please contact our sales team through the website or call us directly, providing the product name and CAS number (65451-89-0).
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