(S)-2-(tert-Butyldiphenylsilanyloxy)propionaldehyde
(S)-2-(tert-Butyldiphenylsilanyloxy)propionaldehyde (CAS 87696-33-1; C19H24O2Si) is a chiral aldehyde featuring a bulky silyl protecting group. This organic building block is instrumental in asymmetric synthesis, enabling the construction of complex stereocenters. It serves as a versatile intermediate in the development of advanced materials and pharmaceutical compounds, offering a reliable starting point for intricate chemical transformations requiring specific stereochemistry. Its utility is primarily in research and development settings.
- IUPAC
- (S)-2-(tert-Butyldiphenylsilyloxy)propanal

Chiral Building Block
This aldehyde is a valuable chiral building block for introducing stereochemistry into organic molecules. It is frequently employed in the synthesis of enantiomerically pure compounds for pharmaceutical and agrochemical research.
Asymmetric Synthesis Intermediate
As an intermediate in asymmetric synthesis, it allows for the stereoselective creation of new chiral centres. Its structure facilitates controlled reactions, leading to specific enantiomers or diastereomers.
Protecting Group Chemistry
The tert-butyldiphenylsilyl (TBS) ether serves as a robust protecting group for the alcohol functionality, stable under a variety of reaction conditions. This allows for selective manipulation of the aldehyde moiety.
Organic Synthesis Reagent
Utilised in complex organic syntheses, this compound acts as a key starting material or intermediate in multi-step synthetic routes for novel molecules and materials.
| Molecular weight | 312.48 |
|---|---|
| Empirical formula | C19H24O2Si |
| Assay | ≥97.0% (GC) |
| Optical activity | [α]/D -17±3°, c = 1 in chloroform |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-2-(tert-Butyldiphenylsilanyloxy)propionaldehyde used for?
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(S)-2-(tert-Butyldiphenylsilanyloxy)propionaldehyde is primarily used as a chiral building block and intermediate in asymmetric synthesis for the development of complex organic molecules, including pharmaceutical compounds and advanced materials.
What is the CAS number and molecular formula for this chemical?
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The CAS number is 87696-33-1 and the molecular formula is C19H24O2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97.0% (GC). This is a research-grade chemical and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling requirements for this product?
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This product requires the use of eyeshields and gloves for safe handling. It is classified under WGK Germany 3, indicating a hazard to water. Always consult the Safety Data Sheet (SDS) before use.
How is (S)-2-(tert-Butyldiphenylsilanyloxy)propionaldehyde typically stored and shipped?
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The product is typically stored at -20°C. Tech Serve Solutions can export this chemical globally to meet your research and manufacturing needs.
How can I request a sample or quote for (S)-2-(tert-Butyldiphenylsilanyloxy)propionaldehyde?
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To request a sample or a quote, please contact our sales team directly through our website or by phone, referencing the product name and CAS number 87696-33-1.
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