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(S)-(+)-2-Butanol

CAS 4221-99-2C2H5CH(OH)CH3Chemical Synthesis

(S)-(+)-2-Butanol (CAS: 4221-99-2), a chiral alcohol with the molecular formula C2H5CH(OH)CH3 and a molecular weight of 74.12 g/mol, is a valuable organic building block. Its specific optical activity makes it particularly useful in asymmetric synthesis and other chemical manufacturing processes requiring enantiopure compounds. TSS supplies this chemical for research and industrial applications.

IUPAC
(S)-(+)-sec-Butyl alcohol
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(S)-(+)-2-Butanol (C2H5CH(OH)CH3) — chemical structure, CAS 4221-99-2; Chemistry, fine chemical supplied by Tech Serve Solutions
AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks
01 /Applications

Chiral Building Block in Synthesis

(S)-(+)-2-Butanol serves as a crucial chiral intermediate in the synthesis of complex organic molecules and pharmaceuticals. Its defined stereochemistry allows for the precise construction of enantiomerically pure target compounds.

Asymmetric Synthesis

This enantiomerically enriched alcohol is employed in asymmetric synthesis reactions, where it can act as a chiral auxiliary or a starting material for creating new chiral centres with high stereoselectivity.

Organic Chemistry Research

As a readily available chiral alcohol, (S)-(+)-2-Butanol is frequently used in academic and industrial research laboratories for developing novel synthetic methodologies and exploring reaction mechanisms.

02 /Properties
Molecular weight74.12
Linear formulaC2H5CH(OH)CH3
Assay≥98.5% (sum of enantiomers, GC)
Boiling point99-100 °C(lit.)
Density0.803 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.397(lit.)n20/D 1.397
Optical activity[α]20/D +14±2°, c = 10% in methanol
Vapour pressure12.5 mmHg (20 °C)
Vapour density2.6 (vs air)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H226Flammable liquid and vapour
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation
  • H336May cause drowsiness or dizziness

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Flash point24 °C / 75.2 °F
Transport (UN / ADR)UN 1120 3 / PGIII
Water hazard class (WGK, DE)1
Hazard codes (EU)Xi
Risk statements (R)10-36/37-67
Safety statements (S)7/9-13-24/25-26-46

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
4221-99-2
Beilstein registry
1718763
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-2-Butanol used for?

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(S)-(+)-2-Butanol is primarily used as a chiral building block in asymmetric synthesis and general organic chemistry research for the preparation of enantiomerically pure compounds.

What are the CAS number and formula for (S)-(+)-2-Butanol?

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The CAS number for (S)-(+)-2-Butanol is 4221-99-2, and its linear formula is C2H5CH(OH)CH3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (S)-(+)-2-Butanol with an assay of ≥98.5% (sum of enantiomers, GC). This product is suitable for research and industrial use; TSS does not represent it as USP, BP, or EP grade.

How should (S)-(+)-2-Butanol be handled safely?

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This substance is flammable (H226) and can cause serious eye irritation (H319) and respiratory irritation (H335) with possible drowsiness or dizziness (H336). Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment.

Is (S)-(+)-2-Butanol shipped internationally?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (S)-(+)-2-Butanol, adhering to all international shipping regulations.

How can I request a quote or sample for (S)-(+)-2-Butanol?

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To request a quote or sample, please contact our sales team via the website or provide your requirements through the product inquiry form.

Need (S)-(+)-2-Butanol in a specific grade or volume?