(S)-(+)-2-Butanol
(S)-(+)-2-Butanol (CAS: 4221-99-2), a chiral alcohol with the molecular formula C2H5CH(OH)CH3 and a molecular weight of 74.12 g/mol, is a valuable organic building block. Its specific optical activity makes it particularly useful in asymmetric synthesis and other chemical manufacturing processes requiring enantiopure compounds. TSS supplies this chemical for research and industrial applications.
- IUPAC
- (S)-(+)-sec-Butyl alcohol

Chiral Building Block in Synthesis
(S)-(+)-2-Butanol serves as a crucial chiral intermediate in the synthesis of complex organic molecules and pharmaceuticals. Its defined stereochemistry allows for the precise construction of enantiomerically pure target compounds.
Asymmetric Synthesis
This enantiomerically enriched alcohol is employed in asymmetric synthesis reactions, where it can act as a chiral auxiliary or a starting material for creating new chiral centres with high stereoselectivity.
Organic Chemistry Research
As a readily available chiral alcohol, (S)-(+)-2-Butanol is frequently used in academic and industrial research laboratories for developing novel synthetic methodologies and exploring reaction mechanisms.
| Molecular weight | 74.12 |
|---|---|
| Linear formula | C2H5CH(OH)CH3 |
| Assay | ≥98.5% (sum of enantiomers, GC) |
| Boiling point | 99-100 °C(lit.) |
| Density | 0.803 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.397(lit.)n20/D 1.397 |
| Optical activity | [α]20/D +14±2°, c = 10% in methanol |
| Vapour pressure | 12.5 mmHg (20 °C) |
| Vapour density | 2.6 (vs air) |


Hazard statements
- H226Flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H336May cause drowsiness or dizziness
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 24 °C / 75.2 °F |
|---|---|
| Transport (UN / ADR) | UN 1120 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37-67 |
| Safety statements (S) | 7/9-13-24/25-26-46 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-Butanol used for?
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(S)-(+)-2-Butanol is primarily used as a chiral building block in asymmetric synthesis and general organic chemistry research for the preparation of enantiomerically pure compounds.
What are the CAS number and formula for (S)-(+)-2-Butanol?
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The CAS number for (S)-(+)-2-Butanol is 4221-99-2, and its linear formula is C2H5CH(OH)CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-2-Butanol with an assay of ≥98.5% (sum of enantiomers, GC). This product is suitable for research and industrial use; TSS does not represent it as USP, BP, or EP grade.
How should (S)-(+)-2-Butanol be handled safely?
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This substance is flammable (H226) and can cause serious eye irritation (H319) and respiratory irritation (H335) with possible drowsiness or dizziness (H336). Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment.
Is (S)-(+)-2-Butanol shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (S)-(+)-2-Butanol, adhering to all international shipping regulations.
How can I request a quote or sample for (S)-(+)-2-Butanol?
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To request a quote or sample, please contact our sales team via the website or provide your requirements through the product inquiry form.
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