[(S)-(−)-2,2′-Bis(di-p-tolylphosphino)-1,1′-binaphthyl]palladium(II) chloride
[(S)-(−)-2,2′-Bis(di-p-tolylphosphino)-1,1′-binaphthyl]palladium(II) chloride (CAS: 215597-19-6) is a chiral palladium complex with the empirical formula C48H40Cl2P2Pd and a molecular weight of 856.10 g/mol. This specialised compound serves as a highly effective catalyst, particularly in asymmetric synthesis, enabling the stereoselective preparation of complex organic molecules with high enantiomeric purity. Its utility is well-documented in academic research for specific cyclisation and oxidation reactions.
- IUPAC
- [PdCl2{(S)-4-tolylbinap}]
- Synonyms
- 215597-19-6C48H40Cl2P2Pd[PdCl2{(S)-4-tolylbinap}]
![[(S)-(−)-2,2′-Bis(di-p-tolylphosphino)-1,1′-binaphthyl]palladium(II) chloride (C48H40Cl2P2Pd) — chemical structure, CAS 215597-19-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F215597-19-6.png&w=3840&q=75)
Asymmetric Catalysis
This palladium complex acts as a chiral catalyst in stereoselective reactions. It is employed in the preparation of complex organic structures where precise control over stereochemistry is essential, such as in the synthesis of chiral intermediates for pharmaceuticals and fine chemicals.
Stereoselective Synthesis
It facilitates the stereoselective synthesis of hydroxymethyldihydronaphthalenone via alkylative ring opening and subsequent transformations. Additionally, it is used in the asymmetric synthesis of cyclopentylindanes through intramolecular cyclisation reactions.
Chiral Ligand Applications
As a derivative of BINAP, this compound functions as a valuable chiral ligand in palladium-catalysed cross-coupling and cyclisation reactions, enabling access to enantiomerically enriched products.
| Molecular weight | 856.10 |
|---|---|
| Empirical formula | C48H40Cl2P2Pd |
| Application | Catalyst for:• Stereoselective preparation of hydroxymethyldihydronaphthalenone via alkylative ring opening of oxabenzonorbornadiene with (PhMe2SiCH2)2Zn followed by hydrogenation and Tamao-Fleming oxidation1• Asymmetric synthesis of cyclopentylindanes via cyclization of bromo- and trifluoromethanesulfonyloxyphenylheptenylmalonate2 |
| Melting point | >300 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [(S)-(−)-2,2′-Bis(di-p-tolylphosphino)-1,1′-binaphthyl]palladium(II) chloride used for?
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This compound is primarily used as a chiral catalyst in asymmetric synthesis, facilitating stereoselective reactions like the synthesis of hydroxymethyldihydronaphthalenone and cyclopentylindanes.
What is the CAS number and formula for this chemical?
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The CAS number is 215597-19-6 and the empirical formula is C48H40Cl2P2Pd.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research-grade material. We do not represent it as meeting any pharmacopoeia standards (e.g., USP, BP, EP) unless explicitly stated in the product specifications.
What are the safety and handling precautions for this compound?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK 2 in Germany, indicating it is hazardous to water.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packs and ships chemicals in compliance with all relevant international regulations for hazardous materials, ensuring safe and secure transport globally.
How can I request a sample or a quote for this product?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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