(S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid
(S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid (CAS 74163-81-8) is a chiral organic compound with the molecular formula C10H11NO2. It serves as a valuable building block in organic synthesis and is particularly relevant in peptide chemistry and the development of unnatural amino acid derivatives. This compound finds applications in chemical biology and synthesis research, contributing to the creation of novel molecular structures.
- Synonyms
- 4-Tetrahydro-3-isoquinolinecarboxylic acid74163-81-8C10H11NO2

Chemical Synthesis
This compound is utilized as a chiral building block in complex organic synthesis pathways. Its defined stereochemistry makes it valuable for constructing specific molecular architectures.
Peptide Chemistry
It serves as a component in the synthesis of modified peptides and peptidomimetics. Its inclusion can introduce unique structural features or alter biological activity.
Unnatural Amino Acid Derivatives
The compound is employed in the preparation of unnatural amino acids, which are critical for expanding the scope of peptide research and drug discovery.
Chemical Biology Research
It can be used as a tool compound or intermediate in studies aimed at understanding biological processes at the molecular level.
| Molecular weight | 177.20 |
|---|---|
| Empirical formula | C10H11NO2 |
| Assay | 97% |
| Optical activity | [α]20/D −168°, c = 1.8 in 1.4 M NaOH |
| Melting point | >300 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid used for?
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(S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid is primarily used in chemical synthesis, peptide chemistry, and as a derivative in unnatural amino acid research. It also finds applications in chemical biology.
What are the CAS number and formula for this compound?
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The CAS number is 74163-81-8, and the molecular formula is C10H11NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance (GHS07) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area.
How is (S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for safe transport. We adhere to all relevant shipping and export regulations for chemical compounds.
How can I request a sample or quote for this product?
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To request a sample or obtain a quotation, please contact our sales department through the methods provided on our website.
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