Ricobendazole

CAS 54029-12-8C12H15N3O3SBiochemicals & Reagents

Ricobendazole (CAS: 54029-12-8; Formula: C12H15N3O3S; Molar Mass: 281.33 g/mol) is a methylcarbamate benzimidazole with broad-spectrum anthelmintic activity. It is a key metabolite of albendazole. Research indicates potential applications in human cancer cell line research, showing induction of apoptosis and cell cycle arrest. Available from Tech Serve Solutions with a purity of ≥98% (HPLC).

IUPAC: Albendazole oxide,Albendazole sulfoxide,Methyl [5-(propane-1-sulfinyl)-1H-benzoimidazol-2-yl]-carbamate

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Ricobendazole (C12H15N3O3S) — chemical structure, CAS 54029-12-8; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Antiparasitic Research

Ricobendazole exhibits broad-spectrum anthelmintic properties, making it valuable for research into parasitic infections and their treatment. Its mechanism involves disruption of parasitic cellular processes.

Cancer Cell Line Studies

This compound has demonstrated potential in research settings to induce apoptosis and arrest the cell cycle in human cancer cell lines, specifically HT-29, suggesting avenues for further oncological investigation.

Metabolite Studies

As a primary metabolite of albendazole, Ricobendazole is essential for studies investigating the metabolic pathways and efficacy of its parent compound in biological systems.

02 /Properties

Molecular weight	281.33
Empirical formula	C12H15N3O3S
Assay	≥98% (HPLC)
Application	Ricobendazole is a methylcarbamate benzimidazole with a broad-spectrum anthelmintic activity. Ricobendazole is a key metabolite of albendazole 1. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting the cell cycle at the G2/M phase.2

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

54029-12-8

Beilstein registry

677664

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Ricobendazole used for?

Ricobendazole is primarily used as an anthelmintic agent with broad-spectrum activity and in research related to cancer cell lines and albendazole metabolism.

What are the CAS number and chemical formula for Ricobendazole?

The CAS number for Ricobendazole is 54029-12-8, and its chemical formula is C12H15N3O3S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Ricobendazole with a minimum purity of ≥98% (HPLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.

What are the safety considerations for handling Ricobendazole?

Ricobendazole is classified as harmful if swallowed (H302). When handling, use appropriate personal protective equipment including a dust mask (N95 type), eyeshields, and gloves.

How is Ricobendazole packed, shipped, and exported?

Ricobendazole is carefully packed to maintain its integrity during transit and is available for export globally by Tech Serve Solutions, adhering to all necessary regulations.