L-(+)-α-Phenylglycine
L-(+)-α-Phenylglycine (CAS 2935-35-5), a chiral amino acid derivative with the formula C8H9NO2 and a molecular weight of 151.16 g/mol, is a key building block. It finds significant utility in chemical synthesis and peptide chemistry. As an unnatural amino acid, it is instrumental in developing novel peptides and pharmaceuticals, contributing to advancements in chemical biology and related fields.
- IUPAC
- (S)-(+)-α-Aminophenylacetic acid

Chemical Synthesis
L-(+)-α-Phenylglycine serves as a chiral auxiliary and a versatile synthon in organic chemistry. Its incorporation allows for the stereoselective synthesis of complex molecules, including pharmaceuticals and fine chemicals.
Peptide Chemistry
This unnatural amino acid is employed in the synthesis of peptides and peptidomimetics. It can introduce specific structural features or enhance the stability and biological activity of peptide-based therapeutics.
Chemical Biology Research
Researchers utilise L-(+)-α-Phenylglycine to probe biological systems and develop novel molecular probes. Its unique structure facilitates the study of protein-ligand interactions and enzyme mechanisms.
| Molecular weight | 151.16 |
|---|---|
| Empirical formula | C8H9NO2 |
| Assay | ≥99.0% (NT) |
| Optical activity | [α]20/D +156±2°, c = 1% in 1 M HCl |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-(+)-α-Phenylglycine used for?
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L-(+)-α-Phenylglycine is used in chemical synthesis, peptide chemistry, and chemical biology research. It is a chiral building block for synthesising complex organic molecules and unnatural peptides.
What are the CAS number and formula for L-(+)-α-Phenylglycine?
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The CAS number for L-(+)-α-Phenylglycine is 2935-35-5, and its empirical formula is C8H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-(+)-α-Phenylglycine with an assay of ≥99.0% (NT). This product is supplied for research and development purposes and is not intended for use in USP, BP, EP, or other pharmacopoeia applications.
How should L-(+)-α-Phenylglycine be handled safely?
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Handling L-(+)-α-Phenylglycine requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Consult the Safety Data Sheet for full details.
How is L-(+)-α-Phenylglycine shipped?
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L-(+)-α-Phenylglycine is securely packaged and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemicals.
How can I request a sample or quote for L-(+)-α-Phenylglycine?
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To request a sample or quote for L-(+)-α-Phenylglycine, please contact our sales team through the website or by telephone, referencing the product CAS number 2935-35-5.
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