(R)(−)-DOI hydrochloride
(R)(−)-DOI hydrochloride (CAS: 82864-02-6), a potent serotonin receptor agonist, is identified by its chemical formula C11H16INO2 · HCl and a molecular weight of 357.62 g/mol. This white solid compound is primarily used in neurochemical research and pharmacology. Its specific activity at serotonin receptors makes it a valuable tool for studying neurotransmission and related physiological processes.
- IUPAC
- (−)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride,(−)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride
- Synonyms
- (−)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride(−)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride
Neuroscience Research Tool
Utilised in pharmacological studies to investigate the function and regulation of serotonin receptors, particularly HTR2A, HTR2B, and HTR2C. Its agonistic properties aid in understanding neurotransmitter pathways and their implications in neurological disorders.
Cell Signaling Studies
Serves as a key reagent for exploring cell signalling cascades mediated by G protein-coupled receptors (GPCRs). Researchers employ it to probe the downstream effects of receptor activation in various cellular models.
Biochemical Assays
Applied in in vitro biochemical assays to quantify receptor binding affinities and functional responses. Its defined purity (≥98% HPLC) ensures reliable and reproducible experimental outcomes.
| Molecular weight | 357.62 |
|---|---|
| Empirical formula | C11H16INO2 · HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | H2O: ≥20 mg/mLethanol: soluble |
| Optical activity | [α]22/D −12.36°, c = 2 in H2O(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | Home Office Schedule 1 |
|---|---|
| Gene Information | human ... HTR2A(3356), HTR2B(3357), HTR2C(3358) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)(−)-DOI hydrochloride used for?
+
(R)(−)-DOI hydrochloride is primarily used as a tool in neuroscience and pharmacological research to study serotonin receptors (HTR2A, HTR2B, HTR2C) and their role in cell signalling and neurotransmission.
What are the CAS number and formula for (R)(−)-DOI hydrochloride?
+
The CAS number for (R)(−)-DOI hydrochloride is 82864-02-6, and its chemical formula is C11H16INO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)(−)-DOI hydrochloride with a purity of ≥98% as determined by HPLC. This product is intended for research and laboratory use, and TSS does not represent it as USP, BP, or EP grade.
How should (R)(−)-DOI hydrochloride be handled safely?
+
Handle (R)(−)-DOI hydrochloride with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. The compound is classified under WGK Germany 3, indicating a hazard to water.
Is (R)(−)-DOI hydrochloride a controlled substance?
+
Yes, (R)(−)-DOI hydrochloride is listed under Home Office Schedule 1 in the UK, indicating it is a controlled substance.
How is (R)(−)-DOI hydrochloride packed and shipped?
+
Our products, including (R)(−)-DOI hydrochloride, are carefully packed and prepared for global export, adhering to all relevant shipping and handling regulations.
How can I request a sample or quote for (R)(−)-DOI hydrochloride?
+
To request a sample or a quote for (R)(−)-DOI hydrochloride, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis