(R)-3-Pyrrolidinol
(R)-3-Pyrrolidinol (CAS: 2799-21-5; Formula: C4H9NO; MW: 87.12) is a chiral heterocyclic building block utilized in chemical synthesis. This enantiomerically pure compound serves as a valuable intermediate in the development of complex organic molecules, particularly in asymmetric synthesis. Its specific stereochemistry makes it crucial for creating stereoselective reactions, leading to pharmaceuticals and other fine chemicals where precise molecular architecture is essential.
- IUPAC
- (R)-3-Hydroxypyrrolidine
Chiral Synthesis
(R)-3-Pyrrolidinol is a key chiral building block used in the synthesis of enantiomerically pure compounds. It enables stereoselective reactions critical for developing advanced pharmaceuticals and agrochemicals.
Pharmaceutical Intermediates
This compound serves as an important intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its defined stereochemistry is vital for the efficacy and safety of the final drug products.
Asymmetric Synthesis
As a chiral alcohol, (R)-3-Pyrrolidinol facilitates asymmetric synthesis, allowing chemists to control the stereochemical outcome of reactions and produce specific enantiomers.
Heterocyclic Chemistry
The pyrrolidine ring structure makes it a useful synthon in heterocyclic chemistry for constructing novel molecular frameworks.
| Molecular weight | 87.12 |
|---|---|
| Empirical formula | C4H9NO |
| Assay | ≥99.0% (sum of enantiomers, GC) |
| Boiling point | 215-216 °C(lit.) |
| Density | 1.078 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.488(lit.)n20/D 1.490 |
| Optical activity | [α]20/D +6.5±1°, c = 3.5% in methanol (as free base) |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-3-Pyrrolidinol used for?
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(R)-3-Pyrrolidinol is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the production of pharmaceuticals and other fine chemicals where specific stereochemistry is required.
What are the CAS number and formula for (R)-3-Pyrrolidinol?
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The CAS number for (R)-3-Pyrrolidinol is 2799-21-5, and its molecular formula is C4H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-3-Pyrrolidinol with an assay of ≥99.0% (sum of enantiomers, GC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should (R)-3-Pyrrolidinol be handled safely?
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Handle (R)-3-Pyrrolidinol with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation. It is classified with GHS07 signal word 'Warning' and hazard statements H315, H319, H335, indicating it can cause skin irritation, serious eye irritation, and respiratory irritation.
How is (R)-3-Pyrrolidinol packed and shipped?
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(R)-3-Pyrrolidinol is typically stored at 2-8°C. TSS exports fine chemicals globally, adhering to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote for (R)-3-Pyrrolidinol?
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To request a sample or a quote for (R)-3-Pyrrolidinol, please contact our sales team via the website or directly by phone or email.
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