(R)-3-Methyl-2-ketopiperazine

CAS 922178-61-8C5H10N2OChemical Synthesis

(R)-3-Methyl-2-ketopiperazine (CAS: 922178-61-8, C5H10N2O) is a chiral heterocyclic compound with a molecular weight of 114.15 g/mol. This piperazine derivative is a valuable building block in asymmetric synthesis and general chemical synthesis. Its specific stereochemistry makes it useful for constructing complex molecules where precise spatial arrangement is critical. Tech Serve Solutions offers this compound for research and development purposes.

IUPAC: (R)-3-Methyl-2-oxo-piperazine

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(R)-3-Methyl-2-ketopiperazine (C5H10N2O) — chemical structure, CAS 922178-61-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPiperazines

01 /Applications

Chiral Building Block in Organic Synthesis

Utilised as a key intermediate in the synthesis of enantiomerically pure compounds. Its defined stereocenter allows for the stereoselective construction of complex molecular architectures in pharmaceuticals and agrochemicals.

Asymmetric Synthesis Applications

Serves as a crucial component in asymmetric synthesis methodologies. It can be incorporated into chiral auxiliaries or directly into target molecules requiring a specific (R)-configuration.

Heterocyclic Chemistry Research

A versatile reagent for exploring novel heterocyclic structures. Its piperazine core and chiral center offer unique opportunities for derivatisation and the development of new chemical entities.

02 /Properties

Molecular weight	114.15
Empirical formula	C5H10N2O
Assay	≥99.0% (GC)
Optical purity	ee: ≥96.0% (HPLC)

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H319Causes serious eye irritation
H334May cause allergy or asthma symptoms if inhaled

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES
P342

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	2
Hazard codes (EU)	Xi
Risk statements (R)	36-43
Safety statements (S)	26-36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

922178-61-8

MDL number

MFCD07373460

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (R)-3-Methyl-2-ketopiperazine used for?

(R)-3-Methyl-2-ketopiperazine is primarily used as a chiral building block in asymmetric synthesis and general chemical synthesis.

What is the CAS number and chemical formula for (R)-3-Methyl-2-ketopiperazine?

The CAS number is 922178-61-8 and the empirical formula (Hill notation) is C5H10N2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (R)-3-Methyl-2-ketopiperazine with an assay of ≥99.0% (GC) and an optical purity of ee: ≥96.0% (HPLC). This product is supplied for research and development and is not represented as USP, EP, BP or pharmaceutical grade.

What are the main hazards associated with (R)-3-Methyl-2-ketopiperazine?

(R)-3-Methyl-2-ketopiperazine is a GHS08 hazard, indicated by the signal word 'Danger'. It carries hazard statements H319 (Causes serious eye irritation) and H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves, is essential during handling.