(R)-(−)-2-Chloromandelic acid
(R)-(−)-2-Chloromandelic acid (CAS: 52950-18-2) is a chiral organic compound with the formula ClC6H4CH(OH)CO2H and a molecular weight of 186.59 g/mol. Produced by BASF, this chemical is primarily used as a valuable building block in asymmetric synthesis and organic chemical synthesis. Its specific stereochemistry makes it an important intermediate for creating complex chiral molecules in research and development settings.

Chiral Building Block
(R)-(−)-2-Chloromandelic acid serves as a key chiral synthon. Its defined stereochemistry is critical for constructing enantiomerically pure target molecules in pharmaceutical and fine chemical research.
Asymmetric Synthesis
This compound is employed in asymmetric synthesis pathways. It can be used to introduce chirality or as a starting material for developing new stereoselective synthetic methodologies.
Organic Synthesis Intermediate
As a versatile organic intermediate, it facilitates the creation of more complex chemical structures. Its functional groups allow for various chemical transformations in multi-step syntheses.
| Molecular weight | 186.59 |
|---|---|
| Linear formula | ClC6H4CH(OH)CO2H |
| Assay | ≥97.5% (HPLC)98% |
| Grade | produced by BASF |
| Optical purity | enantiomeric excess: ≥98.5% |
| Melting point | 119-121 °C(lit.) |


Hazard statements
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-2-Chloromandelic acid used for?
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(R)-(−)-2-Chloromandelic acid is primarily used as a chiral building block and intermediate in asymmetric synthesis and general organic chemical synthesis.
What is the CAS number and chemical formula for (R)-(−)-2-Chloromandelic acid?
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The CAS number is 52950-18-2, and the chemical formula is ClC6H4CH(OH)CO2H.
What grade and purity does Tech Serve Solutions supply for (R)-(−)-2-Chloromandelic acid?
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Tech Serve Solutions supplies (R)-(−)-2-Chloromandelic acid produced by BASF with an assay of ≥97.5% (HPLC) or 98%, and an enantiomeric excess of ≥98.5%. This product is not supplied as USP, BP, or EP grade.
What are the primary safety hazards associated with (R)-(−)-2-Chloromandelic acid?
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(R)-(−)-2-Chloromandelic acid is classified as Danger. It can cause an allergic skin reaction (H317) and serious eye damage (H318). Appropriate personal protective equipment, including gloves and eye protection, should be worn during handling.
How is (R)-(−)-2-Chloromandelic acid packed and shipped?
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This chemical is typically packed in suitable containers for safe transport and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for (R)-(−)-2-Chloromandelic acid?
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To request a sample or a quote for (R)-(−)-2-Chloromandelic acid, please contact our sales team through the website or by email, providing your contact details and intended quantity.
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