(R)-2-Chloro-3-methylbutyric acid
(R)-2-Chloro-3-methylbutyric acid (CAS: 84918-96-7, C5H9ClO2) is a chiral organic building block with a molecular weight of 136.58 g/mol. This carboxylic acid derivative is characterised by its specific optical activity. It serves as a valuable intermediate in asymmetric synthesis and chemical manufacturing processes, enabling the creation of complex chiral molecules. Its defined stereochemistry makes it a key component in specialised chemical research and development.
- IUPAC
- (R)-α-Chloroisovaleric acid
- Synonyms
- (R)-alpha-Chloroisovaleric acid

Asymmetric Synthesis
Utilised as a chiral building block for the stereoselective synthesis of complex organic molecules, where precise control over chirality is essential.
Pharmaceutical Intermediates
Acts as a precursor in the development pathways for active pharmaceutical ingredients (APIs), contributing to the synthesis of chiral drugs.
Organic Synthesis
Employed as a reagent and building block in various organic transformations requiring a chiral carboxylic acid moiety.
Chemical Research
A key compound for academic and industrial research laboratories investigating new synthetic routes and molecular structures.
| Molecular weight | 136.58 |
|---|---|
| Empirical formula | C5H9ClO2 |
| Assay | ≥90% (GC) |
| Density | 1.144 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.443 |
| Optical activity | [α]20/D 0.0 to +1.5°, c = neat |
| Storage temperature | 2-8°C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-2-Chloro-3-methylbutyric acid used for?
+
(R)-2-Chloro-3-methylbutyric acid is primarily used in asymmetric synthesis, as a pharmaceutical intermediate, and in general organic synthesis and chemical research as a chiral building block.
What are the CAS number and chemical formula for this compound?
+
The CAS number is 84918-96-7 and the empirical formula is C5H9ClO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-2-Chloro-3-methylbutyric acid with an assay of ≥90% (GC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should (R)-2-Chloro-3-methylbutyric acid be handled safely?
+
This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including full-face protection and chemically resistant gloves, must be used. Handle in a well-ventilated area and consult the Safety Data Sheet for detailed handling procedures.
How is (R)-2-Chloro-3-methylbutyric acid packed, shipped, and exported?
+
This chemical is shipped as UN 3265, Class 8, Packing Group III, indicating it is a corrosive solid. Tech Serve Solutions handles all export and shipping requirements according to international regulations.
How can I request a sample or quote for (R)-2-Chloro-3-methylbutyric acid?
+
To request a sample or quote, please contact our sales team through the website or by calling the provided number, specifying the required quantity and your shipping details.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis