Q-VD-OPh hydrate
Q-VD-OPh hydrate (CAS 1135695-98-5) is a chemical compound with the formula C26H25F2N3O6 · xH2O. It functions as a potent pancaspase inhibitor, playing a crucial role in the study of apoptosis and cell cycle regulation. Supplied as a white to light brown powder with a molecular weight of 513.49 g/mol on an anhydrous basis, this molecule is essential for research in cell biology and signaling pathways.
- IUPAC
- (3S)-5-(2,6-Difluorophenoxy)-3-[[(2S)-3-methyl-1-oxo-2-[(2-quinolinylcarbonyl)amino]butyl]amino]-4-oxo-pentanoic acid hydrate
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Pancaspase Inhibition in Apoptosis Research
Q-VD-OPh hydrate acts as a broad-spectrum caspase inhibitor, enabling researchers to investigate the role of caspases in programmed cell death (apoptosis) and other cellular processes. Its use allows for the modulation of caspase activity to study protective mechanisms against cellular damage.
Cell Biology and Signaling Studies
This compound is utilized in cell biology research to explore cell signaling pathways and understand cellular responses to various stimuli. Its ability to inhibit caspases makes it valuable for discerning the specific contributions of these enzymes to cellular events.
Neuroscience Research Applications
In neuroscience, Q-VD-OPh hydrate can be employed to study the role of caspases in neuronal cell death and survival. This facilitates research into neurodegenerative diseases and conditions where caspase activity is implicated.
| Molecular weight | 513.49 (anhydrous basis) |
|---|---|
| Empirical formula | C26H25F2N3O6 · xH2O |
| Assay | ≥95% (HPLC) |
| Form | powder |
| Colour | white to light brown |
| Solubility | DMSO: ≥14 mg/mL |
| Storage temperature | −20°C |
| Application | Q-VD-OPh hydrate was used as pancaspase inhibitor to study the protective role of EspZ effector protein against apoptosis and necrosis in human epithelial cells.1 |
| Shipped In | wet ice |
|---|---|
| Storage Condition | desiccated |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Q-VD-OPh hydrate used for?
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Q-VD-OPh hydrate is used as a pancaspase inhibitor to study apoptosis, cell cycle regulation, cell signaling, and in neuroscience research.
What are the CAS number and formula for Q-VD-OPh hydrate?
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The CAS number for the anhydrous form is 1135695-98-5, and its formula is C26H25F2N3O6 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Q-VD-OPh hydrate with an assay of ≥95% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
What are the safety considerations for handling Q-VD-OPh hydrate?
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Q-VD-OPh hydrate has a WGK (Germany) rating of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area.
How is Q-VD-OPh hydrate shipped and stored?
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This product is shipped in wet ice and should be stored desiccated at -20°C.
How can I request a quote or sample for Q-VD-OPh hydrate?
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Please contact the Tech Serve Solutions sales team via our website or direct inquiry channels to request a quote or sample for Q-VD-OPh hydrate.
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