Pyrogallol
Pyrogallol (CAS 87-66-1), a trihydroxybenzene with the formula C6H3(OH)3 and a molar mass of 126.11 g/mol, is a versatile organic compound. It is known for its reducing properties and finds application in analytical chemistry, particularly in preparing extracts for vitamin E and retinol analysis via HPLC. Available from Tech Serve Solutions as an ACS reagent, it is supplied for research and laboratory applications.
- IUPAC
- 1,2,3-Trihydroxybenzene
- Synonyms
- 1,2,3-Trihydroxybenzene
Vitamin E Determination
Pyrogallol serves as a key reagent in preparing endothelial cell extracts. This preparation is crucial for the subsequent determination of vitamin E content using reverse-phase High-Performance Liquid Chromatography (HPLC).
Retinol Analysis
In analytical chemistry, pyrogallol is employed in the preparation of liver extracts. These extracts are then analysed for retinol content using High-Performance Liquid Chromatography (HPLC) methods.
Chemical Synthesis Intermediate
As an organic building block, pyrogallol can be utilised in various chemical synthesis pathways. Its three hydroxyl groups offer reactive sites for derivatisation and further chemical transformations.
| Molecular weight | 126.11 |
|---|---|
| Linear formula | C6H3(OH)3 |
| Assay | ≥98% (HPLC) |
| Grade | ACS reagent |
| Boiling point | 309 °C(lit.) |
| Vapour pressure | 10 mmHg (167.7 °C) |
| Vapour density | 4.4 (vs air) |
| Melting point | 133-134 °C(lit.) |
| Application | Pyrogallol has been used for preparing endothelial cell extract for determining vitamin E content using reverse-phase HPLC.1 It has also been used for preparing liver extracts for retinol analysis by using HPLC.2 |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H341Suspected of causing genetic defects
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-52/53-68 |
| Safety statements (S) | 36/37-61 |
| Cation traces | Fe: ≤0.001%heavy metals (as Pb): ≤5 ppm |
| Anion traces | chloride (Cl-): ≤0.001%sulfate (SO42-): ≤0.005% |
| Ignition residue | ≤0.005% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pyrogallol used for?
+
Pyrogallol is used in analytical chemistry for preparing endothelial cell extracts for vitamin E determination and liver extracts for retinol analysis, both by HPLC. It also serves as an organic building block in chemical synthesis.
What is the CAS number and chemical formula for Pyrogallol?
+
The CAS number for Pyrogallol is 87-66-1, and its chemical formula is C6H3(OH)3.
What grade and purity does Tech Serve Solutions supply for Pyrogallol?
+
Tech Serve Solutions supplies Pyrogallol as an ACS reagent with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Pyrogallol be handled safely?
+
Pyrogallol is harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It is also suspected of causing genetic defects (H412) and is harmful to aquatic life with long-lasting effects. Appropriate personal protective equipment, including dust masks, eyeshields, gloves, and suitable respirator filters, should be used. Handle in a well-ventilated area.
Is Pyrogallol a controlled substance?
+
The provided safety data does not indicate that Pyrogallol is a controlled substance.
How can I request a quote or sample of Pyrogallol?
+
Please contact our sales department via the website or phone to request a quote or sample of Pyrogallol.
How is Pyrogallol packaged and shipped?
+
Pyrogallol is shipped as UN 2811, Hazard Class 6.1, Packing Group III, following relevant transport regulations for chemical export.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis