Purvalanol B

CAS 212844-54-7C20H25ClN6O3Cell Biology

Purvalanol B (CAS 212844-54-7, C20H25ClN6O3) is a research chemical with a molecular weight of 432.90 g/mol. This potent inhibitor is primarily utilised in biochemical research for its specific activity against certain kinase enzymes. It serves as a valuable tool in cell biology and cell signalling studies, particularly those investigating pathways involving cyclin-dependent kinases (CDKs) and other serine/threonine kinases.

IUPAC: (2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol,NG 95

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Purvalanol B (C20H25ClN6O3) — chemical structure, CAS 212844-54-7; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyKinase/Phosphatase Biology

01 /Applications

Cell Biology Research

Purvalanol B is employed as a selective inhibitor in studies exploring cell cycle regulation and proliferation. Its mechanism targets specific kinase enzymes, providing researchers with a tool to dissect cellular processes.

Cell Signalling Investigations

This compound aids in understanding cellular communication pathways by inhibiting key signalling kinases. Researchers use Purvalanol B to investigate downstream effects of kinase activity in various biological contexts.

Kinase Inhibition Studies

As a well-characterised inhibitor, Purvalanol B is used in research focused on serine/threonine kinases and cyclin-dependent kinases (CDKs). It helps to elucidate the functional roles of these enzymes in cellular functions.

02 /Properties

Molecular weight	432.90
Empirical formula	C20H25ClN6O3
Assay	≥97% (HPLC)
Form	solid
Solubility	DMSO: soluble37 mg/mLH2O: insoluble
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

212844-54-7

05 /Additional specifications

Shipped In	dry ice

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Purvalanol B used for?

Purvalanol B is used in biochemical research as a tool for studying cell biology, cell signalling, and kinase inhibition, particularly involving cyclin-dependent kinases (CDKs) and serine/threonine kinases.

What are the CAS number and formula for Purvalanol B?

The CAS number for Purvalanol B is 212844-54-7, and its empirical formula is C20H25ClN6O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Purvalanol B with a purity of e297% by HPLC. This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.

How is Purvalanol B shipped and stored?

Purvalanol B is shipped under dry ice and should be stored at -20°C.

What are the safety considerations for handling Purvalanol B?

When handling Purvalanol B, it is essential to wear eyeshields and gloves. A P1 (EN143) or N95 (US) respirator filter should be used. It is classified under WGK Germany 3, indicating a hazard to water.

How can I request a quote or sample for Purvalanol B?

To request a quote or sample of Purvalanol B, please contact our sales team through the website or by phone, providing the product name and CAS number.