Prostratin
Prostratin (CAS 60857-08-1), a phorbol derivative with the empirical formula C22H30O6 and a molecular weight of 390.47 g/mol, is a powerful activator of protein kinase C (PKC). It serves as a valuable research tool in cell biology, specifically in studies of cell signaling pathways and neuroscience. Its specific mode of action makes it instrumental in understanding cellular responses and regulatory mechanisms.
- IUPAC
- 12-Deoxyphorbol-13-acetate,CCRIS 6292,NSC 623310
- Synonyms
- 12-Deoxyphorbol-13-acetate, CCRIS 6292, NSC 623310
Protein Kinase C Activation
Prostratin functions as a potent activator of protein kinase C, a crucial enzyme family involved in a wide array of cellular processes including growth, differentiation, and survival. It is used to investigate the downstream effects of PKC activation in various cell types.
Cell Signaling Research
This compound is employed to study complex cell signaling cascades. By activating specific PKC isoforms, researchers can elucidate signal transduction pathways relevant to cellular responses and disease mechanisms.
Neuroscience Investigations
In neuroscience research, Prostratin is utilised to explore the role of PKC in neuronal function and development. Its application aids in understanding neuronal plasticity and responses to various stimuli.
| Molecular weight | 390.47 |
|---|---|
| Empirical formula | C22H30O6 |
| Assay | ≥98% (HPLC) |
| Form | white powder |
| Solubility | DMSO: soluble30 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Prostratin used for?
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Prostratin is used in research to activate protein kinase C (PKC), enabling the study of cell signaling pathways, particularly in cell biology and neuroscience.
What are the CAS number and formula for Prostratin?
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Prostratin has the CAS number 60857-08-1 and the empirical formula C22H30O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Prostratin with an assay of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Prostratin be handled and stored?
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Handle Prostratin with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at -20°C.
Is Prostratin a controlled substance?
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The provided data does not indicate that Prostratin is a controlled substance.
How is Prostratin packed and shipped?
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Prostratin is typically supplied as a white powder. TSS exports fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Prostratin?
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To request a sample or quote for Prostratin, please contact the TSS sales team via the website or your designated representative.
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