Propargyl bromide solution
Propargyl bromide solution (CAS: 106-96-7), with the molecular formula HC≡CCH₂Br, is a reactive organic compound supplied by Tech Serve Solutions. It is primarily utilised as a versatile building block in chemical synthesis, particularly for introducing the propargyl group into organic molecules. This solution, typically around 80% in toluene and stabilised with magnesium oxide light, serves as a key intermediate in the development of various complex chemical structures.
- IUPAC
- 3-Bromo-1-propyne
- Synonyms
- 3-Bromo-1-propyne
Organic Synthesis Intermediate
Propargyl bromide solution is a valuable reagent for synthesizing complex organic molecules. Its alkyne functionality allows for diverse reactions, including click chemistry and Sonogashira couplings, making it useful in pharmaceutical and materials science research.
Building Block for Heterocycles
This compound acts as a critical building block for the construction of various heterocyclic compounds. The propargyl group can be readily cyclized or functionalized to create novel ring systems with potential applications in medicinal chemistry.
Alkylation Agent
As a propargylating agent, it is used to introduce the propargyl moiety onto nucleophiles such as alcohols, thiols, and amines. This transformation is fundamental in modifying existing molecules or creating new derivatives with altered properties.
| Molecular weight | 118.96 |
|---|---|
| Linear formula | HC≡CCH2Br |
| Boiling point | 88-90 °C |
| Density | 1.38 g/mL at 20 °C |
| Refractive index | n20/D 1.494 |
| Concentration | ~80% in toluene |
| Storage temperature | 2-8°C |
| Contains / stabiliser | ~0.3% magnesium oxide light as stabilizer |
Hazard statements
- H225Highly flammable liquid and vapour
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P301IF SWALLOWED
- P305IF IN EYES
- P331Do NOT induce vomiting
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 7 °C / 44.6 °F |
| Transport (UN / ADR) | UN 2345 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 11-20/21-25-36/37/38 |
| Safety statements (S) | 16-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Propargyl bromide solution used for?
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Propargyl bromide solution is primarily used as a versatile building block in organic synthesis for introducing the propargyl group and constructing complex organic molecules, including heterocyclic compounds.
What is the CAS number and formula for Propargyl bromide solution?
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The CAS number for Propargyl bromide solution is 106-96-7, and its molecular formula is HC≡CCH₂Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Propargyl bromide solution at approximately 80% concentration in toluene, stabilised with magnesium oxide light. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Propargyl bromide solution be handled?
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Propargyl bromide solution is a highly flammable liquid and toxic substance. Handle with extreme care in a well-ventilated area or fume hood, wearing appropriate personal protective equipment including eyeshields, gloves, and a full-face respirator. Avoid contact with skin, eyes, and clothing, and keep away from heat, sparks, and open flames. Refer to the Safety Data Sheet for detailed handling procedures.
Is Propargyl bromide solution shipped internationally?
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Yes, Tech Serve Solutions specialises in global supply and export of chemicals, including Propargyl bromide solution, adhering to all relevant shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of Propargyl bromide solution, please contact our sales team through the website or by phone, providing your specific requirements.
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