Potassium 3-(trifluoromethyl)phenyltrifluoroborate
Potassium 3-(trifluoromethyl)phenyltrifluoroborate (CAS: 816457-58-6, Formula: C7H4BF6K) is a specialised organoboron compound with a molecular weight of 252.01. This trifluoroborate salt serves as a valuable reagent in organic synthesis, particularly for facilitating Suzuki-Miyaura cross-coupling reactions. Its utility lies in introducing the 3-(trifluoromethyl)phenyl moiety into complex molecular structures, making it a key component in the development of pharmaceuticals and advanced materials.
Suzuki-Miyaura Coupling Reagent
Potassium 3-(trifluoromethyl)phenyltrifluoroborate is employed as a coupling partner in palladium-catalyzed Suzuki-Miyaura reactions. It enables the efficient formation of carbon-carbon bonds by transferring the 3-(trifluoromethyl)phenyl group to aryl or vinyl halides and pseudohalides.
Synthesis of Fluorinated Aromatics
This compound is instrumental in the synthesis of molecules containing the 3-(trifluoromethyl)phenyl substituent. Such fluorinated aromatic motifs are frequently found in active pharmaceutical ingredients (APIs) and agrochemicals due to their unique electronic and lipophilic properties.
Organometallic Chemistry
As a stable trifluoroborate salt, it falls under the umbrella of organometallic reagents used in cross-coupling methodologies. Its defined structure and reactivity profile make it a reliable choice for researchers in academic and industrial settings.
| Molecular weight | 252.01 |
|---|---|
| Empirical formula | C7H4BF6K |
| Assay | 97% |
| Application | Boron trifluoroboronate for Suzuki coupling |
| Melting point | 228.2-230.7 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Potassium 3-(trifluoromethyl)phenyltrifluoroborate primarily used for?
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It is primarily used as a reagent in Suzuki-Miyaura cross-coupling reactions for the introduction of the 3-(trifluoromethyl)phenyl group into organic molecules.
What is the CAS number and chemical formula for this compound?
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The CAS number is 816457-58-6, and the chemical formula is C7H4BF6K.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a minimum purity of 97% as indicated by the assay. We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with this chemical?
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This compound is classified as a Warning, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment and handling procedures are necessary.
Is this chemical available for export?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including Potassium 3-(trifluoromethyl)phenyltrifluoroborate.
How can I request a quote or sample?
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Please contact our sales team directly through our website or by phone to request a quote or to inquire about obtaining a sample for evaluation.
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