POPSO disodium salt
POPSO disodium salt (CAS: 108321-07-9), with the molecular formula C10H20N2O8S2Na2 and a molecular weight of 406.38 g/mol, is a zwitterionic N-substituted derivative of piperazine. It belongs to the Good's buffers family, known for their buffering capacity within the physiological pH range. This compound is particularly effective in biochemical and biological research applications, where stable pH environments are critical for experimental integrity and biological sample preservation.
- IUPAC
- Piperazine-N,N′-bis(2-hydroxypropanesulfonic acid)

Biological Buffering Agent
POPSO disodium salt is utilised as a buffering agent in biological and biochemical research. Its pKa of 7.8 provides effective buffering capacity in the pH range of 7.2 to 8.5, which is suitable for maintaining stable pH in various experimental systems, enzyme assays, and cell culture media.
Biochemical Research
As a Good's buffer, it finds application in a wide array of biochemical studies, including protein purification, electrophoresis, and studies involving enzyme kinetics where pH control is paramount. Its zwitterionic nature minimises interactions with biological macromolecules.
Diagnostic Assays
The consistent pH control offered by POPSO disodium salt makes it valuable in the development and execution of various diagnostic assays, ensuring reproducible results and optimal conditions for biological reactions.
| Molecular weight | 406.38 |
|---|---|
| Linear formula | C10H20N2O8S2Na2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Pka 25 °C | 7.8 |
|---|---|
| Useful Ph Range | 7.2 - 8.5 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is POPSO disodium salt used for?
+
POPSO disodium salt is used as a biological buffering agent in biochemical and biological research. Its pKa of 7.8 allows for effective buffering in the pH range of 7.2–8.5, making it suitable for enzyme assays, cell culture, and protein studies.
What are the CAS number and formula for POPSO disodium salt?
+
The CAS number for POPSO disodium salt is 108321-07-9, and its molecular formula is C10H20N2O8S2Na2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies POPSO disodium salt as a research or technical grade chemical. The specific assay and purity are available upon request or detailed on the Certificate of Analysis. It is not supplied as USP, BP, or EP grade.
How should POPSO disodium salt be handled safely?
+
When handling POPSO disodium salt, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. In situations where airborne dust may be generated, a type N95 (US) or type P1 (EN143) respirator filter should be used. Observe a WGK Germany rating of 3, indicating a high hazard.
Is POPSO disodium salt a controlled substance?
+
The provided data does not indicate that POPSO disodium salt is a controlled or scheduled substance.
How is POPSO disodium salt packaged and exported?
+
POPSO disodium salt is packaged securely for transit and is available for global export by Tech Serve Solutions. Specific packaging details can be confirmed upon order.
How can I request a sample or quote for POPSO disodium salt?
+
To request a sample or a quote for POPSO disodium salt, please contact the Tech Serve Solutions sales team via our website or by phone, providing your specific requirements and delivery details.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis