Poly-D-lysine hydrobromide

CAS 27964-99-4D-Lys-(D-Lys)n-D-Lys · xHBrBiochemicals & Reagents

Poly-D-lysine hydrobromide (CAS: 27964-99-4) is a synthetic polyamino acid used as a cell culture substratum. This lyophilized powder, with a molecular weight of 70,000-150,000, functions as an attachment factor, promoting cell adhesion to surfaces. It is particularly useful when working with cells sensitive to L-lysine or those that digest poly-L-lysine. Supplied by Tech Serve Solutions for research applications.

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Poly-D-lysine hydrobromide (D-Lys-(D-Lys)n-D-Lys · xHBr) — chemical structure, CAS 27964-99-4; Life Science, fine chemical supplied by Tech Serve Solutions

Amino AcidsAttachment FactorsAttachments FactorsBiochemicals and ReagentsCell CultureCore BioreagentsPolyamino AcidsReagents and SupplementsResearch Essentials More...

01 /Applications

Cell Culture Substratum

Poly-D-lysine hydrobromide serves as an effective coating for cell culture surfaces, enhancing cell attachment and growth. It is recommended to use 0.5 - 1.0 mL of a 0.1 mg/mL solution to coat 25 cm² surfaces.

Attachment Factor

As a D-lysine polymer, it acts as a reliable attachment factor, crucial for studies involving cells that may exhibit high uptake or digestion of L-lysine-based polymers. Its positively charged nature promotes adherence of negatively charged cells.

Surface Modification

The polymer can be used to modify surfaces, creating a more hospitable environment for a variety of cell types in research settings. Higher molecular weight variants offer more attachment sites per molecule.

02 /Properties

Linear formula	D-Lys-(D-Lys)n-D-Lys · xHBr
Form	lyophilized powder
Storage temperature	−20°C
Application	Poly-D-lysine polymers can be used in preparing surfaces for cell attachment. The D-lysine polymers can also be used with cells that digest poly-L-lysine polymers and cause an excessive uptake of L-lysine. This product is recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/mL solution to coat 25 cm2. Lower molecular weight versions of the product are less viscous, but high more molecular weight versions provide more attachment sites per molecule.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

27964-99-4

MDL number

MFCD00131934

PubChem substance

24898764

05 /Additional specifications

Product Line	BioReagent
Mol Wt	mol wt 70,000-150,000

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Poly-D-lysine hydrobromide used for?

Poly-D-lysine hydrobromide is primarily used as a cell culture substratum and attachment factor to promote cell adhesion to surfaces in research applications.

What is the CAS number and formula for Poly-D-lysine hydrobromide?

The CAS number for Poly-D-lysine hydrobromide is 27964-99-4. Its linear formula is <sc>D</sc>-Lys-(<sc>D</sc>-Lys)<sub>n</sub>-<sc>D</sc>-Lys · xHBr.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Poly-D-lysine hydrobromide as a BioReagent. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade.

How should Poly-D-lysine hydrobromide be handled safely?

When handling Poly-D-lysine hydrobromide, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance has a WGK Germany rating of 3.

How is Poly-D-lysine hydrobromide shipped?

Poly-D-lysine hydrobromide is typically lyophilized and shipped under refrigeration. Please contact our export department for specific international shipping details.

How can I request a quote or sample?

To request a quote or a sample of Poly-D-lysine hydrobromide, please visit the product page on our website and use the 'Request a Quote' or 'Request Sample' button, or contact our sales team directly.