Pipecolinic acid
Pipecolinic acid (CAS 535-75-1), with the molecular formula C6H11NO2 and a molecular weight of 129.16 g/mol, is a cyclic amino acid derivative. It serves as a valuable building block in chemical synthesis and peptide chemistry. As a proline analogue, it is frequently employed in the development of novel peptides and in chemical biology research. Tech Serve Solutions offers this compound for laboratory and research applications.
- IUPAC
- (±)-Piperidine-2-carboxylic acid,2-Piperidinecarboxylic acid,Homoproline,Pipecolic acid free base
- Synonyms
- (±)-Piperidine-2-carboxylic acid2-Piperidinecarboxylic acidHomoprolinePipecolic acid free base

Chemical Synthesis
Pipecolinic acid is utilised as a chiral building block in the synthesis of complex organic molecules. Its structure allows for diverse chemical modifications, making it useful in constructing novel compounds.
Peptide Chemistry
As an unnatural amino acid derivative, pipecolinic acid is incorporated into peptides to modify their structure, stability, and biological activity. It is a key component in creating peptidomimetics and novel peptide analogues.
Chemical Biology Research
This compound finds application in chemical biology for probing biological systems and developing new molecular probes. Its unique structural features can help in understanding protein-ligand interactions.
Proline Derivative Studies
Pipecolinic acid serves as a valuable reference compound and synthon in studies involving proline and its derivatives. Researchers use it to explore structure-activity relationships in various biological contexts.
| Molecular weight | 129.16 |
|---|---|
| Empirical formula | C6H11NO2 |
| Assay | 98% |
| Melting point | 282 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pipecolinic acid used for?
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Pipecolinic acid is used in chemical synthesis, peptide chemistry, chemical biology research, and as a proline derivative in various studies.
What is the CAS number and formula for Pipecolinic acid?
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The CAS number for Pipecolinic acid is 535-75-1, and its empirical formula is C6H11NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pipecolinic acid with an assay of 98%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Pipecolinic acid be handled safely?
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Pipecolinic acid can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Is Pipecolinic acid a controlled substance?
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The provided data does not indicate that Pipecolinic acid is a controlled substance.
How is Pipecolinic acid packed and shipped?
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Pipecolinic acid is carefully packed for shipping and export in compliance with relevant regulations to ensure product integrity and safety during transit.
How can I request a sample or quote for Pipecolinic acid?
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To request a sample or quote for Pipecolinic acid, please contact our sales department through the website or by phone. Our team will be happy to assist you.
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