α-Phenylglycinonitrile hydrochloride

CAS 53941-45-0C6H5CH(NH2)CN · HClChemical Synthesis

α-Phenylglycinonitrile hydrochloride (CAS: 53941-45-0), with the linear formula C6H5CH(NH2)CN · HCl and a molecular weight of 168.62 g/mol, is a valuable intermediate. It is primarily utilised in chemical synthesis, particularly within peptide chemistry and the development of unnatural amino acid derivatives. This compound serves as a crucial building block for researchers and chemists engaged in advanced organic and pharmaceutical research.

IUPAC: α-Aminophenylacetonitrile hydrochloride
Synonyms: α-Aminophenylacetonitrile hydrochloride

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α-Phenylglycinonitrile hydrochloride (C6H5CH(NH2)CN · HCl) — chemical structure, CAS 53941-45-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryPhenylglycine Derivatives

01 /Applications

Chemical Synthesis Intermediate

Serves as a key intermediate in the synthesis of complex organic molecules. Its structure makes it suitable for introducing phenylglycine moieties into larger structures.

Peptide Chemistry

Used in the construction of peptides, especially those incorporating non-proteinogenic amino acids. Facilitates the synthesis of modified peptides with unique properties.

Unnatural Amino Acid Synthesis

A valuable precursor for creating unnatural amino acid derivatives. These derivatives are essential for research in medicinal chemistry and biochemical studies.

Pharmaceutical Research

Employed in the early stages of drug discovery and development, allowing for the synthesis of novel pharmaceutical candidates.

02 /Properties

Molecular weight	168.62
Linear formula	C6H5CH(NH2)CN · HCl
Assay	≥95% (AT)
Melting point	~170 °C (dec.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

53941-45-0

MDL number

MFCD00013022

Beilstein registry

4155088

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is α-Phenylglycinonitrile hydrochloride used for?

α-Phenylglycinonitrile hydrochloride is used as an intermediate in chemical synthesis, peptide chemistry, and for the preparation of unnatural amino acid derivatives in pharmaceutical research.

What are the CAS number and chemical formula for α-Phenylglycinonitrile hydrochloride?

The CAS number is 53941-45-0, and the chemical formula is C6H5CH(NH2)CN · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies α-Phenylglycinonitrile hydrochloride with an assay of ≥95% (AT). This compound is not supplied as USP, BP, EP, or any pharmacopoeia grade.

How should α-Phenylglycinonitrile hydrochloride be handled safely?

Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid contact with skin and eyes, and avoid dust formation. It is classified as a Warning with hazards H315 (Causes skin irritation) and H319 (Causes serious eye irritation).