Phenyl-d5-boronic acid
Phenyl-d5-boronic acid (CAS: 215527-70-1), with the chemical formula C6D5B(OH)2 and a molecular weight of 126.96 g/mol, is a deuterated aryl boronic acid derivative. Utilised primarily in organic synthesis, it serves as a valuable building block in cross-coupling reactions, particularly Suzuki-Miyaura couplings. Its deuterated nature makes it useful in mechanistic studies and as an internal standard in mass spectrometry, aiding in precise quantitative analysis within research and development settings.
Suzuki-Miyaura Coupling Reagent
Phenyl-d5-boronic acid is a key reagent in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds. This allows for the synthesis of complex biaryl compounds and other substituted aromatic systems.
Deuterated Building Block
The presence of deuterium atoms in Phenyl-d5-boronic acid makes it an excellent choice for applications requiring isotopic labelling. It is used in mechanistic studies to trace reaction pathways and in the development of labelled pharmaceutical intermediates.
Internal Standard in Mass Spectrometry
Due to its precise mass difference from its non-deuterated counterpart, Phenyl-d5-boronic acid can serve as an effective internal standard. This is crucial for accurate quantification of related compounds in analytical chemistry and research.
Organic Synthesis Intermediate
As a versatile intermediate, this compound is employed in the synthesis of various fine chemicals and research compounds. It provides a reliable route to introduce a deuterated phenyl group into target molecules.
| Molecular weight | 126.96 |
|---|---|
| Linear formula | C6D5B(OH)2 |
| Assay | 98% (CP) |
| Melting point | 217-220 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Isotopic Purity | 98 atom % D |
|---|---|
| Mass Shift | M+5 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenyl-d5-boronic acid primarily used for?
+
Phenyl-d5-boronic acid is primarily used as a deuterated building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, and as an internal standard in mass spectrometry for mechanistic studies and quantitative analysis.
What are the CAS number and chemical formula for Phenyl-d5-boronic acid?
+
The CAS number for Phenyl-d5-boronic acid is 215527-70-1, and its chemical formula is C6D5B(OH)2.
What grade and purity does Tech Serve Solutions supply for Phenyl-d5-boronic acid?
+
Tech Serve Solutions supplies Phenyl-d5-boronic acid with an assay of 98% (CP) and an isotopic purity of 98 atom % D. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for Phenyl-d5-boronic acid?
+
Phenyl-d5-boronic acid is classified with GHS07 symbol and a 'Warning' signal word, bearing hazard statement H302 (Harmful if swallowed). Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area and avoid ingestion.
Is Phenyl-d5-boronic acid available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and Phenyl-d5-boronic acid can be exported to qualified customers worldwide.
How can I request a sample or quote for Phenyl-d5-boronic acid?
+
To request a sample or a quote for Phenyl-d5-boronic acid, please use the contact form on our website or contact our sales department directly with your inquiry.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis