Phenyl[3-(trifluoromethyl)phenyl]iodonium triflate
Phenyl[3-(trifluoromethyl)phenyl]iodonium triflate (CAS: 905718-46-9; C14H9F6IO3S; MW: 498.18) is a hypervalent iodine reagent. It functions as a versatile electrophilic trifluoromethylating and arylating agent in organic synthesis. Its utility is primarily found in academic research and industrial process development for the introduction of trifluoromethyl groups and aryl moieties into various organic molecules, contributing to the synthesis of complex structures.
- IUPAC
- Phenyl[3-(trifluoromethyl)phenyl]iodonium trifluoromethanesulfonate,[3-(Trifluoromethyl)phenyl]phenyliodonium triflate
- Synonyms
- Phenyl[3-(trifluoromethyl)phenyl]iodonium trifluoromethanesulfonate[3-(Trifluoromethyl)phenyl]phenyliodonium triflate
![Phenyl[3-(trifluoromethyl)phenyl]iodonium triflate (C14H9F6IO3S) — chemical structure, CAS 905718-46-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F905718-46-9.png&w=3840&q=75)
Electrophilic Trifluoromethylation
This compound serves as an effective reagent for introducing the trifluoromethyl (CF3) group into nucleophilic substrates. The CF3 group is a crucial motif in pharmaceuticals and agrochemicals due to its ability to modulate lipophilicity and metabolic stability.
Electrophilic Arylation
It can act as a source of the phenyl and 3-(trifluoromethyl)phenyl groups for arylation reactions. This allows for the efficient construction of biaryl compounds and other complex aromatic systems.
Organic Synthesis Intermediate
As a specialized synthetic reagent, it finds application in multi-step syntheses where precise functional group introduction is required. Its reactivity profile makes it suitable for advanced chemical transformations.
| Molecular weight | 498.18 |
|---|---|
| Empirical formula | C14H9F6IO3S |
| Assay | ≥98% (HPLC) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenyl[3-(trifluoromethyl)phenyl]iodonium triflate used for?
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Phenyl[3-(trifluoromethyl)phenyl]iodonium triflate is primarily used as a reagent for electrophilic trifluoromethylation and arylation in organic synthesis. It is valuable for introducing trifluoromethyl and aryl groups into organic molecules.
What are the CAS number and formula for Phenyl[3-(trifluoromethyl)phenyl]iodonium triflate?
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The CAS number is 905718-46-9 and the empirical formula is C14H9F6IO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenyl[3-(trifluoromethyl)phenyl]iodonium triflate with a purity of ≥98% (HPLC). This product is not graded as USP, BP, EP, or for pharmaceutical, nutraceutical, or food use.
What are the safety and handling considerations for this chemical?
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This compound is classified as a Warning (GHS07) with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, ensuring good ventilation. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes.
How is Phenyl[3-(trifluoromethyl)phenyl]iodonium triflate packed and shipped?
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Tech Serve Solutions exports chemicals globally, adhering to all necessary shipping and handling regulations. Please contact us for specific packaging and export details.
How can I request a sample or a quote?
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You can request a sample or a quote by contacting our sales team through the website or by calling our customer service. Please reference the product name and CAS number.
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