Phenobarbital
Phenobarbital (CAS: 50-06-6, C12H12N2O3) is a barbiturate derivative with a molecular weight of 232.24 g/mol. It functions as a central nervous system depressant. Historically, it has been used for its sedative, hypnotic, and anticonvulsant properties. Phenobarbital is a controlled substance in many jurisdictions due to its potential for dependence and misuse.
- IUPAC
- 5-Ethyl-5-phenyl-2,4,6-pyrimidinetrione,5-Ethyl-5-phenylbarbituric acid,Luminal
- Synonyms
- 5-Ethyl-5-phenyl-2,4,6-pyrimidinetrione5-Ethyl-5-phenylbarbituric acidLuminal

Anticonvulsant Therapy
Phenobarbital is employed in the management of various seizure disorders, including epilepsy. Its mechanism of action involves enhancing inhibitory neurotransmission.
Sedative and Hypnotic Agent
Historically, Phenobarbital has been used for its sedative effects to manage anxiety and insomnia, though its use for these indications has largely been superseded by safer alternatives.
Research Chemical
This compound serves as a valuable tool in pharmacological and neuroscientific research to study GABAergic pathways and CNS depressant effects.
| Molecular weight | 232.24 |
|---|---|
| Empirical formula | C12H12N2O3 |


Hazard statements
- H301Toxic if swallowed
- H317May cause an allergic skin reaction
- H351Suspected of causing cancer
- H360D
Precautionary statements
- P201Obtain special instructions before use
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 61-25-40-43 |
| Safety statements (S) | 53-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule IV; Home Office Schedule 3; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Canada |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenobarbital used for?
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Phenobarbital is primarily used as an anticonvulsant for seizure disorders and historically as a sedative and hypnotic. It is also used in research settings.
What is the CAS number and chemical formula for Phenobarbital?
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The CAS number for Phenobarbital is 50-06-6, and its chemical formula is C12H12N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Phenobarbital in a technical/research grade. We do not represent this product as USP, BP, EP, or any other pharmacopoeia standard.
What are the primary safety concerns when handling Phenobarbital?
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Phenobarbital is a highly toxic substance, indicated by GHS06 and GHS08 symbols and a 'Danger' signal word. It carries hazard statements H301 (Toxic if swallowed), H317 (May cause an allergic skin reaction), H351 (Suspected of causing cancer), and H360D (May damage the unborn child). Strict adherence to safety protocols, including appropriate personal protective equipment like gloves, eyeshields, and respiratory protection, is essential.
Is Phenobarbital a controlled substance?
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Yes, Phenobarbital is a controlled substance. It is listed under US DEA Schedule IV and is regulated in other jurisdictions, with specific restrictions on availability, including being unavailable from Canada.
How is Phenobarbital packed, shipped, and exported by TSS?
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Phenobarbital is carefully packed according to relevant regulations for hazardous materials. TSS is a global supplier and exporter of fine chemicals and reagents, adhering to international shipping standards for controlled substances.
How can I request a sample or quote for Phenobarbital?
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To request a sample or obtain a quote for Phenobarbital, please contact our sales team directly through our website or by phone. Provide your specific requirements and shipping details.
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