[pGlu5, D-Trp7,9,10]-Substance P Fragment 5-11
[pGlu5, D-Trp7,9,10]-Substance P Fragment 5-11 (CAS: 143675-79-0) is a synthetic peptide fragment derived from Substance P. With the molecular formula C57H64N12O9S and a molecular weight of 1093.26, this compound functions as an antagonist. It is primarily utilized in research settings for studies in cell biology, cell signaling, neuroscience, and peptide research, particularly concerning tachykinin pathways.
- IUPAC
- pGlu-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2
- Synonyms
- [pGlu5, D-Trp7,9,10]-Substance P Fragment 5-1110]-Substance P Fragment 5-11C57H64N12O9S143675-79-0
![[pGlu5, D-Trp7,9,10]-Substance P Fragment 5-11 (C57H64N12O9S) — chemical structure, CAS 143675-79-0; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F143675-79-0.png&w=3840&q=75)
Neuroscience Research
Investigates the roles of tachykinins and their receptors in neuronal function, pain perception, and neuroinflammation. This fragment acts as a tool to probe these complex signaling pathways.
Cell Signaling Studies
Used to understand intracellular communication mechanisms related to neuropeptide signaling. Its antagonistic properties can help elucidate the downstream effects of Substance P activation.
Peptide-Based Drug Discovery
Serves as a reference compound or lead structure in the development of novel therapeutic agents targeting tachykinin receptors for various physiological and pathological conditions.
Cell Biology Investigations
Applicable in studies examining cellular responses to neuropeptides, including cellular trafficking, receptor binding, and signal transduction within different cell types.
| Molecular weight | 1093.26 |
|---|---|
| Empirical formula | C57H64N12O9S |
| Assay | ≥90% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [pGlu5, D-Trp7,9,10]-Substance P Fragment 5-11 used for?
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[pGlu5, D-Trp7,9,10]-Substance P Fragment 5-11 is used as an antagonist in research for cell biology, cell signaling, neuroscience, and peptide studies, particularly those involving tachykinins.
What are the CAS number and formula for [pGlu5, D-Trp7,9,10]-Substance P Fragment 5-11?
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The CAS number is 143675-79-0 and the empirical formula is C57H64N12O9S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥90% (HPLC). It is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should [pGlu5, D-Trp7,9,10]-Substance P Fragment 5-11 be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet for comprehensive handling information. The compound has a WGK Germany rating of 3.
How is this chemical shipped from Tech Serve Solutions?
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This product is stored at -20°C and is carefully packed and exported by Tech Serve Solutions to maintain its integrity during transit.
How can I request a sample or a quote for this product?
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Please contact our sales team directly via our website or by phone to request a sample or obtain a quotation for [pGlu5, D-Trp7,9,10]-Substance P Fragment 5-11.
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