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Perfluorobutyryl chloride

CAS 375-16-6CF3CF2CF2COClChemical Synthesis

Perfluorobutyryl chloride (CAS: 375-16-6), with the linear formula CF 3 CF 2 CF 2 COCl and a molecular weight of 232.48 g/mol, is a fluorinated organic compound. It serves as a valuable intermediate and building block in chemical synthesis. This acid halide is primarily utilised in the creation of specialised fluoropolymers and other complex organic molecules, contributing to advancements in materials science and chemical research.

IUPAC
Heptafluorobutyryl chloride
Synonyms
Heptafluorobutyryl chloride
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Perfluorobutyryl chloride (CF3CF2CF2COCl) — chemical structure, CAS 375-16-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Acid HalidesBuilding BlocksCarbonyl CompoundsChemical SynthesisFluorinated Building BlocksOrganic Building Blocks
01 /Applications

Fluoropolymer Synthesis

Used in the preparation of novel fluoropolymers, such as ethylcellulose perfluorobutyrate, for applications like gas-exchange membranes.

Organic Synthesis Intermediate

Acts as a building block for the synthesis of various organic compounds, including heterocyclic structures like 2-perfluoroalkylbenzothiazoles.

Research and Development

Employed in laboratory settings for the development of new materials and chemical entities requiring perfluorinated moieties.

02 /Properties
Molecular weight232.48
Linear formulaCF3CF2CF2COCl
Assay98%
Boiling point39 °C(lit.)
Density1.556 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.3(lit.)
Vapour pressure7.22 psi (20 °C)
Storage temperature2-8°C
ApplicationPerfluorobutyryl chloride has been used in the preparation of:• ethylcellulose perfluorobutyrate, non-thrombogenic novel fluoropolymer for gas-exchange membranes1• 2-perfluoroalkylbenzothiazole2
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US)
Transport (UN / ADR)UN 3265 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
375-16-6
MDL number
MFCD00000707
PubChem substance
24855618
Beilstein registry
1790269
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Perfluorobutyryl chloride used for?

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Perfluorobutyryl chloride is used as a building block in organic synthesis, particularly for preparing fluoropolymers like ethylcellulose perfluorobutyrate and compounds such as 2-perfluoroalkylbenzothiazoles.

What is the CAS number and formula for Perfluorobutyryl chloride?

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The CAS number is 375-16-6 and the linear formula is CF 3 CF 2 CF 2 COCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Perfluorobutyryl chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.

How should Perfluorobutyryl chloride be handled safely?

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Perfluorobutyryl chloride is classified as Danger, causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including face shields, gloves, and respiratory protection, is essential. Handle in a well-ventilated area and refer to the safety data sheet for detailed handling procedures.

How is Perfluorobutyryl chloride packed and shipped?

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The product is shipped as UN 3265, Hazard Class 8, Packing Group II, indicating it is a corrosive material. Specific packaging complies with international shipping regulations. TSS is a global supplier and exporter.

How can I request a quote or sample for Perfluorobutyryl chloride?

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To request a quote or sample, please contact our sales team through the website or by phone. Provide your contact details and the quantity required.

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