Perfluorobutyric acid
Perfluorobutyric acid (CAS 375-22-4), molecular formula CF3CF2CF2COOH, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- Edman Reagent No. 3,HFBA,Heptafluorobutyric acid,Perfluorobutyric acid

| Molecular weight | 214.04 |
|---|---|
| Linear formula | CF3CF2CF2COOH |
| Assay | 98% |
| Boiling point | 120 °C/755 mmHg(lit.) |
| Density | 1.645 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.3(lit.) |
| Vapour pressure | ~10 mmHg (25 °C) |
| Vapour density | 7 (vs air) |
| Application | Perfluorobutyric acid was used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins1. It was used as ion pairing reagent in preparative and analytical reserved phase HPLC of underivatised peptides2. |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 35 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Perfluorobutyric acid?
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Perfluorobutyric acid (CAS 375-22-4), molecular formula CF3CF2CF2COOH, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of Perfluorobutyric acid does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Perfluorobutyric acid in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of Perfluorobutyric acid?
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Perfluorobutyric acid has CAS number 375-22-4 and molecular formula CF3CF2CF2COOH. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for Perfluorobutyric acid?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of Perfluorobutyric acid ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should Perfluorobutyric acid be stored?
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Store Perfluorobutyric acid in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is Perfluorobutyric acid used for?
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Perfluorobutyric acid is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for Perfluorobutyric acid?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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