Pentamethylenebis(magnesium bromide) solution
Pentamethylenebis(magnesium bromide) solution (CAS 23708-48-7), with the linear formula BrMg(CH2)5MgBr and a molecular weight of 278.55 g/mol, is a valuable organometallic reagent. Supplied as a 0.5 M solution in Tetrahydrofuran (THF), it functions as a powerful difunctional Grignard reagent. This compound is primarily utilised in organic synthesis for introducing pentamethylene linkers and in the preparation of complex molecules within the chemical and pharmaceutical industries.
- IUPAC
- Pentane-1,5-di(magnesium bromide)
- Synonyms
- Pentane-1,5-diylbis(magnesium bromide)1,5-Dibromopentane magnesium dibromide1,5-Bis(bromomagnesio)pentane
Organic Synthesis
Utilised as a difunctional Grignard reagent to introduce a five-carbon chain (pentamethylene group) into organic molecules. It facilitates carbon-carbon bond formation in the synthesis of various organic compounds and intermediates.
Polymer Chemistry
Can be employed in the synthesis of specific polymers where a linear alkyl di-halide functionality is required for polymerization reactions or for modifying polymer structures.
Pharmaceutical Intermediate Synthesis
Serves as a key building block in the multi-step synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs) where precise chain extension is needed.
Organometallic Chemistry Research
A reagent of interest in academic and industrial research for exploring new synthetic methodologies and developing novel organometallic complexes.
| Molecular weight | 278.55 |
|---|---|
| Linear formula | BrMg(CH2)5MgBr |
| Density | 0.999 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P422
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pentamethylenebis(magnesium bromide) solution used for?
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Pentamethylenebis(magnesium bromide) solution is primarily used in organic synthesis as a difunctional Grignard reagent to introduce a pentamethylene linker, and in the synthesis of pharmaceutical intermediates and complex organic molecules.
What is the CAS number and formula for Pentamethylenebis(magnesium bromide) solution?
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The CAS number is 23708-48-7, and the linear formula is BrMg(CH2)5MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in Tetrahydrofuran (THF). We do not claim USP, BP, EP, or any pharmacopoeia grade; this product is intended for laboratory and research use.
How should Pentamethylenebis(magnesium bromide) solution be handled safely?
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This solution is a Danger hazard: Highly flammable liquid and vapour (H225). Contact with water liberates flammable gases, may intensify fire (H261). Causes severe skin burns and eye damage (H314). May cause respiratory irritation (H335). It reacts violently with water and may form explosive peroxides. Handle under an inert atmosphere, avoid ignition sources, and use appropriate personal protective equipment including eyeshields, face shields, chemical-resistant gloves, and a suitable respirator.
How is this chemical packed and shipped?
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This product is shipped according to UN 3399, Hazard Class 4.3, Packing Group II regulations for pyrophoric liquids, organometallic compounds, or metal alkyls, liquid. Please contact us for specific packaging and shipping details for export.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team through the website or by phone, referencing the product name and CAS number 23708-48-7.
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