Oxolinic acid
Oxolinic acid (CAS: 14698-29-4), with the molecular formula C13H11NO5 and a molecular weight of 261.23 g/mol, is a synthetic quinolone antibiotic. It is primarily utilised in scientific research for its antibacterial properties, including studies on DNA winding and coiling, dopaminergic neurotransmission, and the investigation of transmissible antibiotic resistance mechanisms in bacteria such as E. coli and Salmonella enterica. It also aids in the isolation of Gardnerella vaginalis.
- IUPAC
- 5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid
Antibacterial Research
Oxolinic acid is employed in microbiological research to study bacterial resistance mechanisms, particularly those involving quinolones and fluoroquinolones. Its ability to inhibit DNA gyrase makes it valuable for investigating DNA supercoiling and unwinding processes in bacteria.
Neurotransmission Studies
This compound serves as a research tool for investigating dopaminergic neurotransmission. Its application in this area allows scientists to explore the complex pathways and interactions within the nervous system.
Bacterial Isolation
Oxolinic acid is a selective agent used in culture media for the isolation of specific bacteria, such as Gardnerella vaginalis. This application is crucial in diagnostic microbiology for identifying causative agents of infection.
DNA Synthesis Interference Studies
Utilised in biochemical research, Oxolinic acid helps scientists understand how bacterial DNA replication is disrupted. It is instrumental in exploring the mechanisms by which antibiotics interfere with essential cellular processes.
| Molecular weight | 261.23 |
|---|---|
| Empirical formula | C13H11NO5 |
| Storage temperature | 2-8°C |
| Application | Oxolinic acid is a quinolone antibiotic used for studies on DNA winding and coiling and for studies on dopaminergic neurotransmission processes. It is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia coli and Salmonella enterica. It is added to culture medium for the isolation of Gardnerella vaginalis1. |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Oxolinic acid used for?
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Oxolinic acid is used for studies on DNA winding and coiling, dopaminergic neurotransmission, investigating bacterial resistance mechanisms in E. coli and Salmonella enterica, and for the isolation of Gardnerella vaginalis.
What are the CAS number and formula for Oxolinic acid?
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The CAS number for Oxolinic acid is 14698-29-4, and its empirical formula is C13H11NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Oxolinic acid as a research chemical. The specific assay and purity are detailed in the product specifications. TSS does not represent this product as USP, BP, or EP grade.
How should Oxolinic acid be handled and stored?
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Oxolinic acid is harmful if swallowed (H302) and may cause respiratory irritation. It should be handled with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Store in a cool, dry place at 2-8°C.
Is Oxolinic acid a controlled substance?
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Based on the provided data, Oxolinic acid is not listed as a controlled substance. However, users should always comply with local regulations.
How can I request a sample or quote for Oxolinic acid?
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To request a sample or a quote for Oxolinic acid, please contact our sales department through the website or by phone. We export globally.
What are the shipping and packaging details for Oxolinic acid?
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Oxolinic acid is carefully packaged to ensure safe transit and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
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