Octafluoroacetophenone
Octafluoroacetophenone (CAS: 652-22-2), with the linear formula C6F5COCF3 and a molecular weight of 264.07 g/mol, is a fluorinated ketone. This compound is recognised for its utility as a building block in organic synthesis. It is a valuable intermediate for creating more complex fluorinated molecules, finding applications in research and development settings. TSS supplies Octafluoroacetophenone with an assay of 97%.

Organic Synthesis Intermediate
Octafluoroacetophenone serves as a key intermediate in the synthesis of complex fluorinated organic compounds. Its reactive carbonyl group and pentafluorophenyl moiety allow for diverse chemical transformations.
Fluorochemical Research
This compound is employed in research laboratories focused on the development of novel fluorinated materials and pharmaceuticals. It enables the introduction of perfluoroalkyl and pentafluorophenyl groups into target molecules.
Building Block for Specialty Chemicals
As a C7-C8 building block, it is utilised in the creation of specialty chemicals where specific fluorination patterns are required. Its unique structure facilitates the design of molecules with tailored properties.
| Molecular weight | 264.07 |
|---|---|
| Linear formula | C6F5COCF3 |
| Assay | 97% |
| Boiling point | 130-131 °C(lit.) |
| Density | 1.609 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.394(lit.) |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 1224C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Octafluoroacetophenone used for?
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Octafluoroacetophenone is primarily used as an intermediate in organic synthesis and for research in fluorochemicals, serving as a building block for more complex fluorinated molecules.
What are the CAS number and chemical formula for Octafluoroacetophenone?
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The CAS number for Octafluoroacetophenone is 652-22-2, and its linear formula is C6F5COCF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Octafluoroacetophenone with an assay of 97%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should Octafluoroacetophenone be handled safely?
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Octafluoroacetophenone is a flammable liquid and vapour (H226). Handle with care, using appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Store away from ignition sources.
Is Octafluoroacetophenone a controlled substance?
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The provided data does not indicate that Octafluoroacetophenone (CAS: 652-22-2) is a controlled substance.
How is Octafluoroacetophenone packed, shipped, and exported?
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Octafluoroacetophenone is packed and shipped according to relevant regulations for flammable liquids (UN 1224C 3 / PGIII). TSS is experienced in global export of chemical products.
How can I request a sample or quote for Octafluoroacetophenone?
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To request a sample or a quote for Octafluoroacetophenone, please contact the Tech Serve Solutions sales team through our website or by phone.
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