O-Methyl-L-threonine
O-Methyl-L-threonine (CAS: 4144-02-9; Formula: C5H11NO3; Molar Mass: 133.15 g/mol) is a modified amino acid derivative. As a non-proteinogenic amino acid, it serves as a valuable building block in peptide synthesis and as a research chemical in biochemical studies. Its unique structure allows for the exploration of altered peptide properties and functionalities in chemical biology and synthetic chemistry.
- IUPAC
- L-Threonine methyl ether
- Synonyms
- L-Threonine methyl ether

Peptide Synthesis
O-Methyl-L-threonine is employed as a non-natural amino acid in solid-phase or solution-phase peptide synthesis. Its incorporation can modulate peptide structure, stability, and biological activity, aiding in the development of novel peptides with tailored properties.
Biochemical Research
Utilised in biochemical research to investigate the role of modified amino acids in biological systems. It can be used to probe enzyme mechanisms, protein folding, or to create peptide analogues for drug discovery.
Chemical Biology
Serves as a tool in chemical biology for developing probes or modified biomolecules. Its presence can help elucidate biological pathways or create new functionalities in complex molecular systems.
Organic Synthesis
Acts as a chiral building block in the synthesis of complex organic molecules. Its stereochemistry can be leveraged in asymmetric synthesis routes for pharmaceuticals or other fine chemicals.
| Molecular weight | 133.15 |
|---|---|
| Empirical formula | C5H11NO3 |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-Methyl-L-threonine used for?
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O-Methyl-L-threonine is primarily used in peptide synthesis, biochemical research, chemical biology studies, and as a chiral building block in organic synthesis.
What is the CAS number and formula for O-Methyl-L-threonine?
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The CAS number for O-Methyl-L-threonine is 4144-02-9, and its molecular formula is C5H11NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-Methyl-L-threonine for research and laboratory use. The specific assay and purity are detailed on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for O-Methyl-L-threonine?
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According to GHS regulations, O-Methyl-L-threonine requires careful handling. Personal protective equipment, including eyeshields and gloves, is recommended. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The WGK Germany classification is 3, indicating a hazard to water.
How is O-Methyl-L-threonine shipped and exported?
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O-Methyl-L-threonine is available for domestic and international export. It is typically stored at 2-8°C. Please contact our sales team for specific shipping and export documentation requirements.
How can I request a sample or quote for O-Methyl-L-threonine?
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To request a sample or a quotation for O-Methyl-L-threonine, please contact our dedicated sales team via the website or direct email, providing your specific requirements and shipping details.
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