nor-Binaltorphimine dihydrochloride
nor-Binaltorphimine dihydrochloride (CAS: 105618-26-6) is a potent and selective kappa opioid receptor antagonist. With the molecular formula C40H43N3O6 · 2HCl and a molecular weight of 734.71 g/mol, this compound is a valuable tool in neuroscience research. It is widely used to investigate the role of kappa opioid receptors in pain perception, addiction, and mood regulation, and to study downstream signaling pathways.
- IUPAC
- nor-BNI dihydrochloride
Kappa Opioid Receptor Antagonism
Used as a selective antagonist to block the activity of kappa opioid receptors (KORs). This allows researchers to elucidate the specific physiological and behavioral roles mediated by KORs in various biological systems.
Neuroscience Research
Essential for studying the involvement of the endogenous opioid system and KORs in areas such as pain, stress, addiction, and mood disorders. It helps in differentiating KOR-mediated effects from those of other opioid receptors.
Cell Signaling Studies
Employed to investigate the intracellular signaling cascades activated by kappa opioid receptor binding, providing insights into G protein-coupled receptor (GPCR) downstream effects.
| Molecular weight | 734.71 |
|---|---|
| Empirical formula | C40H43N3O6 · 2HCl |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... OPRK1(4986) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is nor-Binaltorphimine dihydrochloride used for?
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nor-Binaltorphimine dihydrochloride is primarily used as a selective kappa opioid receptor antagonist in neuroscience research to study pain, addiction, and mood regulation, as well as to investigate cell signaling pathways.
What is the CAS number and formula for nor-Binaltorphimine dihydrochloride?
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The CAS number is 105618-26-6 and the molecular formula is C40H43N3O6 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies nor-Binaltorphimine dihydrochloride as a research-grade chemical. We do not represent it as USP, BP, EP, or other pharmacopoeial grades. Purity information is available on the product's Certificate of Analysis.
How should nor-Binaltorphimine dihydrochloride be handled?
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Handle with care. This compound is a potential irritant to the skin, eyes, and respiratory tract. Wear appropriate personal protective equipment, including gloves, eye protection, and work in a well-ventilated area or fume hood.
Is nor-Binaltorphimine dihydrochloride a controlled substance?
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Based on the provided data, nor-Binaltorphimine dihydrochloride is not listed as a controlled substance. However, regulations can vary by jurisdiction, and users should confirm local compliance.
How is this product shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, adhering to all necessary regulations for safe and compliant packaging and shipping worldwide.
How can I request a sample or quote?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for nor-Binaltorphimine dihydrochloride.
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