NKY80

CAS 299442-43-6C12H11N3O2Cell Biology

NKY80 (CAS: 299442-43-6), with the molecular formula C12H11N3O2 and a molecular weight of 229.23 g/mol, is a potent inhibitor of adenylyl cyclase. This compound is a valuable tool in cell biology research, particularly for investigating cell signaling pathways, neuroscience, and cyclic nucleotide metabolism. It plays a crucial role in understanding G protein-coupled receptor activity and downstream signaling cascades.

IUPAC: 2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone

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NKY80 (C12H11N3O2) — chemical structure, CAS 299442-43-6; Life Science, fine chemical supplied by Tech Serve Solutions

Adenylyl Cyclase InhibitorsCell BiologyCyclic Nucleotide Metabolism

01 /Applications

Adenylyl Cyclase Inhibition

NKY80 serves as a selective inhibitor of adenylyl cyclase, enabling researchers to study the role of cyclic AMP (cAMP) production in various cellular processes. Its application is key to dissecting signal transduction pathways.

Cell Signaling Research

As a modulator of cyclic nucleotide metabolism, NKY80 is instrumental in elucidating complex cell signaling networks. It aids in understanding the mechanisms underlying cellular responses in neuroscience and other biological fields.

G Protein and Cyclic Nucleotide Studies

This compound facilitates research into the interplay between G proteins and cyclic nucleotides, such as cAMP. Researchers utilize NKY80 to investigate the downstream effects of adenylyl cyclase activity.

02 /Properties

Molecular weight	229.23
Empirical formula	C12H11N3O2
Assay	≥98% (HPLC)
Solubility	DMSO: ≥30 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

299442-43-6

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is NKY80 primarily used for?

NKY80 is primarily used as an adenylyl cyclase inhibitor for research in cell biology, cell signaling, neuroscience, and cyclic nucleotide metabolism.

What is the CAS number and formula for NKY80?

The CAS number for NKY80 is 299442-43-6, and its molecular formula is C12H11N3O2.

What grade and purity does Tech Serve Solutions supply for NKY80?

Tech Serve Solutions supplies NKY80 with a purity of ≥98% as determined by HPLC. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should NKY80 be handled and stored?

NKY80 is classified as acutely toxic (H301) and requires careful handling. Store at 2-8°C. Follow strict safety protocols, including appropriate personal protective equipment, when handling this substance. Dispose of it according to hazardous waste regulations.

How is NKY80 packaged and shipped?

NKY80 is packaged and exported according to international regulations for hazardous materials, including UN 2811 classification. Please contact us for specific shipping and export details.