Nicardipine hydrochloride
Nicardipine hydrochloride (CAS: 54527-84-3), with the molecular formula C26H29N3O6 · HCl and a molecular weight of 515.99, is a yellow powder. This dihydropyridine derivative functions as a calcium channel modulator, primarily recognised for its role in vasodilation. It is frequently employed in research settings for its biochemical properties and as a reference standard in analytical chemistry.
- IUPAC
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid ethyl ester hydrochloride,YC-93
- Synonyms
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-[methyl(phenylmethyl)amino]-3,5-pyridinedicarboxylic acid ethyl ester hydrochloride,YC-93
Calcium Channel Modulator Research
Nicardipine hydrochloride serves as a valuable tool in pharmacological research investigating L-type calcium channels. Its ability to block calcium influx is instrumental in understanding cellular signalling pathways and cardiovascular physiology.
Biochemical and Reagent Use
As a bioactive small molecule, it is utilised in biochemical assays and as a reagent in cell biology studies. Its specific mechanism of action makes it a useful standard for comparing other calcium channel blockers.
Analytical Standard
With a purity of ≥98%, Nicardipine hydrochloride is suitable for use as an analytical reference standard in quality control and research laboratories, aiding in the identification and quantification of related substances.
| Molecular weight | 515.99 |
|---|---|
| Empirical formula | C26H29N3O6 · HCl |
| Assay | ≥98% |
| Form | powder |
| Colour | yellow |
| Solubility | DMSO: ~1 mg/mL0.1 M NaOH: insolubleH2O: slightly solublemethanol: soluble |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nicardipine hydrochloride used for?
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Nicardipine hydrochloride is used in pharmacological and biochemical research as a calcium channel modulator, particularly for investigating L-type calcium channels and cellular signalling pathways.
What is the CAS number and formula for Nicardipine hydrochloride?
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The CAS number for Nicardipine hydrochloride is 54527-84-3, and its formula is C26H29N3O6 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nicardipine hydrochloride with an assay of ≥98%. We do not represent this product as meeting any pharmacopoeial standards (e.g., USP, BP, EP).
How should Nicardipine hydrochloride be handled and stored?
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Nicardipine hydrochloride is a Danger compound (GHS06) that is toxic if swallowed, in contact with skin, or if inhaled (H301-H311-H331). It requires careful handling with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator. Store at 2-8°C.
Is Nicardipine hydrochloride a controlled substance?
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The provided data does not indicate that Nicardipine hydrochloride is a controlled substance.
How are Nicardipine hydrochloride products packed and shipped?
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Nicardipine hydrochloride is typically supplied as a yellow powder. For export, it is packaged according to international shipping regulations for hazardous materials (UN 2811 6.1 / PGIII).
How can I request a sample or quote for Nicardipine hydrochloride?
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To request a sample or quote for Nicardipine hydrochloride, please contact our sales department via the website or direct telephone enquiry.
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